Aortic arch replacement with prophylactic aortic arch debranching during type A acute aortic dissection repair: initial experience with 23 patients. 2011

Mattia Glauber, and Michele Murzi, and Pierandrea Farneti, and Stefano Bevilacqua, and Massimiliano Mariani, and Andrea Tognarelli, and Tommaso Gasbarri, and Sergio Berti
Department of Adult Cardiac Surgery, G. Pasquinucci Heart Hospital, Monasterio Fondation-CNR, Via Aurelia Sud 54100, Massa, Italy.

OBJECTIVE To improve the long-term results of acute type A dissection repair, we developed a technique that combines radical surgical resection, and, at the same time, creates a safe and long landing zone for subsequent endovascular procedure on the descending aorta. METHODS Since November 2006, 23 patients (62 ± 13 years) underwent aortic arch replacement concomitant with prophylactic debranching of the supra-aortic vessels, with a specially designed arch graft. The technique consists of replacing the ascending aorta and the aortic arch, and, at the same time, relocating the origin of the supra-aortic vessels just above the sinotubular junction creating a long and safe proximal landing zone for subsequent stent-graft deployment. Perfusion was antegrade through the ascending aorta during cooling and through the vascular prosthesis during rewarming. Distal arch anastomosis was performed under moderate hypothermic circulatory arrest for 25 ± 7 min and antegrade selective cerebral perfusion (46 ± 14 min). Cardiopulmonary bypass and aortic cross-clamp time were 138 ± 46 and 63 ± 22 min. RESULTS Hospital mortality was 4.3% (1/23). Postoperative morbidity includes five acute renal failures and four lung failures. No major neurological complications were observed. At follow-up (22±10 months), survival was 100% and two patients required an endovascular thoracic aorta repair for aneurysmal enlargement. In both cases, the stent grafts were successfully released in the landing zone created at the time of primary repair. CONCLUSIONS Our technique extends the suitability of endovascular therapies during type A acute dissection repair, creating a long and stable landing zone that allows safe performance of a second endovascular step if needed, both in the short- and long term.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D012008 Recurrence The return of a sign, symptom, or disease after a remission. Recrudescence,Relapse,Recrudescences,Recurrences,Relapses
D012086 Reoperation A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery. Revision, Joint,Revision, Surgical,Surgery, Repeat,Surgical Revision,Repeat Surgery,Revision Surgery,Joint Revision,Revision Surgeries,Surgery, Revision
D001807 Blood Vessel Prosthesis Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels. Vascular Prosthesis,Blood Vessel Prostheses,Tissue-Engineered Vascular Graft,Graft, Tissue-Engineered Vascular,Grafts, Tissue-Engineered Vascular,Prostheses, Blood Vessel,Prostheses, Vascular,Prosthesis, Blood Vessel,Prosthesis, Vascular,Tissue Engineered Vascular Graft,Tissue-Engineered Vascular Grafts,Vascular Graft, Tissue-Engineered,Vascular Grafts, Tissue-Engineered,Vascular Prostheses,Vessel Prostheses, Blood,Vessel Prosthesis, Blood
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000208 Acute Disease Disease having a short and relatively severe course. Acute Diseases,Disease, Acute,Diseases, Acute
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

Mattia Glauber, and Michele Murzi, and Pierandrea Farneti, and Stefano Bevilacqua, and Massimiliano Mariani, and Andrea Tognarelli, and Tommaso Gasbarri, and Sergio Berti
June 2020, Journal of cardiothoracic and vascular anesthesia,
Mattia Glauber, and Michele Murzi, and Pierandrea Farneti, and Stefano Bevilacqua, and Massimiliano Mariani, and Andrea Tognarelli, and Tommaso Gasbarri, and Sergio Berti
October 2025, JTCVS open,
Mattia Glauber, and Michele Murzi, and Pierandrea Farneti, and Stefano Bevilacqua, and Massimiliano Mariani, and Andrea Tognarelli, and Tommaso Gasbarri, and Sergio Berti
March 2000, The Journal of thoracic and cardiovascular surgery,
Mattia Glauber, and Michele Murzi, and Pierandrea Farneti, and Stefano Bevilacqua, and Massimiliano Mariani, and Andrea Tognarelli, and Tommaso Gasbarri, and Sergio Berti
December 2015, The Annals of thoracic surgery,
Mattia Glauber, and Michele Murzi, and Pierandrea Farneti, and Stefano Bevilacqua, and Massimiliano Mariani, and Andrea Tognarelli, and Tommaso Gasbarri, and Sergio Berti
February 2024, Annals of vascular surgery,
Mattia Glauber, and Michele Murzi, and Pierandrea Farneti, and Stefano Bevilacqua, and Massimiliano Mariani, and Andrea Tognarelli, and Tommaso Gasbarri, and Sergio Berti
January 2020, The Journal of thoracic and cardiovascular surgery,
Mattia Glauber, and Michele Murzi, and Pierandrea Farneti, and Stefano Bevilacqua, and Massimiliano Mariani, and Andrea Tognarelli, and Tommaso Gasbarri, and Sergio Berti
September 2023, Indian journal of thoracic and cardiovascular surgery,
Mattia Glauber, and Michele Murzi, and Pierandrea Farneti, and Stefano Bevilacqua, and Massimiliano Mariani, and Andrea Tognarelli, and Tommaso Gasbarri, and Sergio Berti
February 2018, The Annals of thoracic surgery,
Mattia Glauber, and Michele Murzi, and Pierandrea Farneti, and Stefano Bevilacqua, and Massimiliano Mariani, and Andrea Tognarelli, and Tommaso Gasbarri, and Sergio Berti
November 1994, The Annals of thoracic surgery,
Mattia Glauber, and Michele Murzi, and Pierandrea Farneti, and Stefano Bevilacqua, and Massimiliano Mariani, and Andrea Tognarelli, and Tommaso Gasbarri, and Sergio Berti
October 2025, JTCVS techniques,
Copied contents to your clipboard!