Biomaterial Database

Nucleotide sequence of the human melanoma growth stimulatory activity (MGSA) gene. 1990

N E Baker, and G Kucera, and A Richmond

Department of Veterans Affairs, Nashville, TN.

UI	MeSH Term	Description	Entries
D008545	Melanoma	A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)	Malignant Melanoma,Malignant Melanomas,Melanoma, Malignant,Melanomas,Melanomas, Malignant
D008969	Molecular Sequence Data	Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.	Sequence Data, Molecular,Molecular Sequencing Data,Data, Molecular Sequence,Data, Molecular Sequencing,Sequencing Data, Molecular
D009363	Neoplasm Proteins	Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.	Proteins, Neoplasm
D005796	Genes	A category of nucleic acid sequences that function as units of heredity and which code for the basic instructions for the development, reproduction, and maintenance of organisms.	Cistron,Gene,Genetic Materials,Cistrons,Genetic Material,Material, Genetic,Materials, Genetic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001483	Base Sequence	The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.	DNA Sequence,Nucleotide Sequence,RNA Sequence,DNA Sequences,Base Sequences,Nucleotide Sequences,RNA Sequences,Sequence, Base,Sequence, DNA,Sequence, Nucleotide,Sequence, RNA,Sequences, Base,Sequences, DNA,Sequences, Nucleotide,Sequences, RNA
D016385	TATA Box	A conserved A-T rich sequence which is contained in promoters for RNA polymerase II. The segment is seven base pairs long and the nucleotides most commonly found are TATAAAA.	Hogness Box,Box, Hogness,Box, TATA
D054360	Chemokine CXCL1	A CXC chemokine with specificity for CXCR2 RECEPTORS. It has growth factor activities and is implicated as a oncogenic factor in several tumor types.	CXCL1 Chemokine,Chemokine (C-X-C Motif) Ligand 1,GROalpha Protein,Gro-alpha Protein,Growth-Related Oncogene alpha Protein,MGSA-alpha Chemokine,Melanoma Growth Stimulatory Activity, alpha Protein,Neutrophil-Activating Protein 3,CXCL1, Chemokine,Chemokine, CXCL1,Chemokine, MGSA-alpha,Gro alpha Protein,Growth Related Oncogene alpha Protein,MGSA alpha Chemokine,Neutrophil Activating Protein 3
D054426	Chemokine CXCL2	A CXC chemokine that is synthesized by activated MONOCYTES and NEUTROPHILS. It has specificity for CXCR2 RECEPTORS.	CXCL2 Chemokine,Chemokine (C-X-C Motif) Ligand 2,LDNCF-2,MIP-2 Chemokine,MIP-2alpha,MIP2alpha,Macrophage Inflammatory Protein 2,Macrophage Inflammatory Protein-2alpha,CXCL2, Chemokine,Chemokine, CXCL2,Chemokine, MIP-2,Inflammatory Protein-2alpha, Macrophage,MIP 2 Chemokine,MIP 2alpha,Macrophage Inflammatory Protein 2alpha
D019743	Chemokines, CXC	Group of chemokines with paired cysteines separated by a different amino acid. CXC chemokines are chemoattractants for neutrophils but not monocytes.	C-X-C Chemokine,CXC Chemokine,CXC Chemokines,alpha-Chemokine,alpha-Chemokines,C-X-C Chemokines,C X C Chemokine,Chemokine, C-X-C,Chemokine, CXC,Chemokines, C-X-C,alpha Chemokine,alpha Chemokines