Dexamethasone suppression test and depressive symptoms in bereaved children: a preliminary report. 1990

E B Weller, and R A Weller, and M A Fristad, and J M Bowes
Department of Psychiatry and Neuroscience, Ohio State University, Columbus 43210.

Eighteen bereaved children and adolescents were assessed using the dexamethasone suppression test (DST) and the Diagnostic Interview for Children and Adolescents 4 weeks following parental death. Thirty-nine percent had a positive (nonsuppressed) DST. DST-positive subjects reported more DSM-III-R depressive symptoms (6.3 +/- 2.9 vs. 3.9 +/- 2.7, means +/- SD) than DST-negative subjects. Most frequently reported symptoms included dysphoria, loss of interest, sleep disturbance, appetite disturbance, psychomotor disturbance, and morbid and suicidal ideation. Post-dexamethasone cortisol levels were significantly correlated with the total number of depressive symptoms and suicidal ideation.

UI MeSH Term Description Entries
D008297 Male Males
D008426 Maternal Deprivation Prolonged separation of the offspring from the mother. Deprivation, Maternal,Deprivations, Maternal,Maternal Deprivations
D010333 Paternal Deprivation Prolonged separation of the offspring from the father. Deprivation, Paternal,Deprivations, Paternal,Paternal Deprivations
D010552 Personality Assessment The determination and evaluation of personality attributes by interviews, observations, tests, or scales. Articles concerning personality measurement are considered to be within scope of this term. Assessment, Personality,Assessments, Personality,Personality Assessments
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002667 Child Reactive Disorders Reactions to an event or set of events which are considered to be of pathological degree, that have not developed into a neurosis, psychosis, or personality disorder with fixed patterns. Child Reactive Disorder,Reactive Disorder, Child
D003863 Depression Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders. Depressive Symptoms,Emotional Depression,Depression, Emotional,Depressive Symptom,Symptom, Depressive
D003907 Dexamethasone An anti-inflammatory 9-fluoro-glucocorticoid. Hexadecadrol,Decaject,Decaject-L.A.,Decameth,Decaspray,Dexasone,Dexpak,Hexadrol,Maxidex,Methylfluorprednisolone,Millicorten,Oradexon,Decaject L.A.
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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