Biomaterial Database

Immediate contact hypersensitivity to acrylic acid. 1990

J F Fowler

University of Louisville School of Medicine, Kentucky.

A chemical worker developed acute generalized urticaria after working with acrylate compounds in a laboratory. Immediate-hypersensitivity testing to acrylic acid yielded a severe local reaction. Testing with other acrylate compounds was negative. Re-exposure in the work-place to vapors of acrylic acid resulted in generalized urticaria. With the cooperation of the employer, the patient moved to a marketing job with no contact with acrylic acid and has remained free of urticaria since.

UI	MeSH Term	Description	Entries
D006969	Hypersensitivity, Immediate	Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.	Atopic Hypersensitivity,Hypersensitivity, Atopic,Hypersensitivity, Type I,IgE-Mediated Hypersensitivity,Type I Hypersensitivity,Atopic Hypersensitivities,Hypersensitivities, Atopic,Hypersensitivities, IgE-Mediated,Hypersensitivities, Immediate,Hypersensitivities, Type I,Hypersensitivity, IgE-Mediated,IgE Mediated Hypersensitivity,IgE-Mediated Hypersensitivities,Immediate Hypersensitivities,Immediate Hypersensitivity,Type I Hypersensitivities
D008297	Male		Males
D009783	Dermatitis, Occupational	A recurrent contact dermatitis caused by substances found in the work place.	Occupational Dermatitis,Dermatosis, Industrial,Industrial Dermatosis,Dermatitides, Occupational,Dermatoses, Industrial,Industrial Dermatoses,Occupational Dermatitides
D010328	Patch Tests	Skin tests in which the sensitizer is applied to a patch of cotton cloth or gauze held in place for approximately 48-72 hours. It is used for the elicitation of a contact hypersensitivity reaction.	Patch Testing,Patch Test,Patch Testings,Test, Patch,Testing, Patch,Testings, Patch,Tests, Patch
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000179	Acrylates	Derivatives of acrylic acid (the structural formula CH2
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D014581	Urticaria	A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.	Hives,Urticarial Wheals,Urticarial Wheal,Urticarias,Wheal, Urticarial,Wheals, Urticarial