[Defective autologous mixed lymphocyte reaction (AMLR) in gastric cancer patients]. 1990

M Iwahashi, and H Tanimura, and H Yamaue, and T Tsunoda, and M Tani
Department of Gastroenterological Surgery, Wakayama Medical College.

Autologous mixed lymphocyte reaction (AMLR) is an important reaction regulating the immune system in the various diseases. This is the first report investigating AMLR not only in peripheral blood but also in the spleen of gastric cancer patients. AMLR in the spleen of gastric cancer patients was significantly suppressed compared with that of peripheral blood of gastric cancer patients and patients without cancer. In investigation of AMLR composed of peripheral blood cells and spleen cells of gastric cancer patient, AMLR on splenic non-T cells as a stimulator was significantly suppressed compared with peripheral blood non-T cells as a stimulator. It suggests that abnormalities of non-T cells caused suppression of AMLR in the spleen of gastric cancer patients.

UI MeSH Term Description Entries
D007959 Lymphocyte Culture Test, Mixed Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens. Leukocyte Culture Test, Mixed,Mixed Lymphocyte Culture Test,Mixed Lymphocyte Reaction,Mixed Leukocyte Culture Test,Mixed Leukocyte Reaction,Leukocyte Reaction, Mixed,Leukocyte Reactions, Mixed,Lymphocyte Reaction, Mixed,Lymphocyte Reactions, Mixed,Mixed Leukocyte Reactions,Mixed Lymphocyte Reactions
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013154 Spleen An encapsulated lymphatic organ through which venous blood filters.
D013274 Stomach Neoplasms Tumors or cancer of the STOMACH. Cancer of Stomach,Gastric Cancer,Gastric Neoplasms,Stomach Cancer,Cancer of the Stomach,Gastric Cancer, Familial Diffuse,Neoplasms, Gastric,Neoplasms, Stomach,Cancer, Gastric,Cancer, Stomach,Cancers, Gastric,Cancers, Stomach,Gastric Cancers,Gastric Neoplasm,Neoplasm, Gastric,Neoplasm, Stomach,Stomach Cancers,Stomach Neoplasm

Related Publications

M Iwahashi, and H Tanimura, and H Yamaue, and T Tsunoda, and M Tani
October 1988, Clinical and experimental immunology,
M Iwahashi, and H Tanimura, and H Yamaue, and T Tsunoda, and M Tani
January 1988, Archivum immunologiae et therapiae experimentalis,
M Iwahashi, and H Tanimura, and H Yamaue, and T Tsunoda, and M Tani
June 1997, Clinical and experimental immunology,
M Iwahashi, and H Tanimura, and H Yamaue, and T Tsunoda, and M Tani
January 1992, Journal of gastroenterology and hepatology,
M Iwahashi, and H Tanimura, and H Yamaue, and T Tsunoda, and M Tani
June 1989, Gut,
M Iwahashi, and H Tanimura, and H Yamaue, and T Tsunoda, and M Tani
November 1989, Clinical and experimental immunology,
M Iwahashi, and H Tanimura, and H Yamaue, and T Tsunoda, and M Tani
September 1984, Cellular immunology,
M Iwahashi, and H Tanimura, and H Yamaue, and T Tsunoda, and M Tani
August 1986, Journal of clinical periodontology,
M Iwahashi, and H Tanimura, and H Yamaue, and T Tsunoda, and M Tani
July 1982, Gastroenterology,
M Iwahashi, and H Tanimura, and H Yamaue, and T Tsunoda, and M Tani
March 1984, Scandinavian journal of immunology,
Copied contents to your clipboard!