[Pseudo-hyperaldosteronism caused by licorice. Pathogenetic considerations and presentation of a clinical case]. 1990

F Lorenzin, and C Degen, and A Milani, and M Siciliano, and L Rossi
Università Cattolica del Sacro Cuore di Roma, Istituto di Patologia Medica.

A case of pseudo-hyperaldosteronism secondary to prolonged daily ingestion of liquorice is reported. Extreme severity of hypokalemia and of the ensuing neuro-muscular impairment characterized this case. The pathogenetic features leading to the glycyrrhizic acid dependent sodium retention are thoroughly discussed, on the basis of the latest literature. The authors stress the fact that public opinion is to a large extent unaware of risks due to prolonged ingestion of liquorice derivatives.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D006034 Glycyrrhetinic Acid An oleanolic acid from GLYCYRRHIZA that has some antiallergic, antibacterial, and antiviral properties. It is used topically for allergic or infectious skin inflammation and orally for its aldosterone effects in electrolyte regulation. Enoxolone,Glycyrrhetic Acid,Rhetinic Acid,Uralenic Acid,Arthrodont,Glyciram,Glycyram,Jintan,Po 12,12, Po,Acid, Glycyrrhetic,Acid, Glycyrrhetinic,Acid, Rhetinic,Acid, Uralenic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006929 Hyperaldosteronism A condition caused by the overproduction of ALDOSTERONE. It is characterized by sodium retention and potassium excretion with resultant HYPERTENSION and HYPOKALEMIA. Aldosteronism,Conn Syndrome,Conn's Syndrome,Primary Hyperaldosteronism,Conns Syndrome,Hyperaldosteronism, Primary,Syndrome, Conn,Syndrome, Conn's

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