New noninvasive index of the left ventricular inotropic state. 1990

D Huml, and M Buksa
Department of Internal Medicine, Energoinvest's Institute for Health Protection, Sarajevo.

In order to confirm in clinical material a new contractile index, the systolic circumferential wall stress/end systolic muscle index ratio (SCS/ESMI), there were compared two groups of patients with pressure overload ventricular hypertrophy, with and without global compliance disturbances (Group B1 = 36; Group B2 = 28) and two groups of age and body surface area-matched healthy individuals (Group A1 = 36; Group A2 = 28). The new index of the contractile or muscle function, the SCS/ESMI ratio, was so effective in the research sample as the systolic circumferential wall stress/cavitary volume ratio, the SCS/ESVI. The product of the systolic contractile index, the SCS/ESVI, and ejection fraction (SCI X EF), as an integrated left ventricular parameter, showed that the ejection or pump function reduction was artificial in patients with an increased afterload and normal preload. The confidence limit for the SCI X EF on the level of 95% is 3.5, and for the product of the new systolic muscle index and ejection fraction, the SMI X EF, is 99. The inaugurated functional parameters could serve for revealing "false positive" cardiac failure or they could reveal the true reduction of the muscle contractile cardiac function by the artificially increased and "normal" ejection phase indices.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009200 Myocardial Contraction Contractile activity of the MYOCARDIUM. Heart Contractility,Inotropism, Cardiac,Cardiac Inotropism,Cardiac Inotropisms,Contractilities, Heart,Contractility, Heart,Contraction, Myocardial,Contractions, Myocardial,Heart Contractilities,Inotropisms, Cardiac,Myocardial Contractions
D006332 Cardiomegaly Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES. Cardiac Hypertrophy,Enlarged Heart,Heart Hypertrophy,Heart Enlargement,Cardiac Hypertrophies,Enlargement, Heart,Heart Hypertrophies,Heart, Enlarged,Hypertrophies, Cardiac,Hypertrophies, Heart,Hypertrophy, Cardiac,Hypertrophy, Heart
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013318 Stroke Volume The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume. Ventricular Ejection Fraction,Ventricular End-Diastolic Volume,Ventricular End-Systolic Volume,Ejection Fraction, Ventricular,Ejection Fractions, Ventricular,End-Diastolic Volume, Ventricular,End-Diastolic Volumes, Ventricular,End-Systolic Volume, Ventricular,End-Systolic Volumes, Ventricular,Fraction, Ventricular Ejection,Fractions, Ventricular Ejection,Stroke Volumes,Ventricular Ejection Fractions,Ventricular End Diastolic Volume,Ventricular End Systolic Volume,Ventricular End-Diastolic Volumes,Ventricular End-Systolic Volumes,Volume, Stroke,Volume, Ventricular End-Diastolic,Volume, Ventricular End-Systolic,Volumes, Stroke,Volumes, Ventricular End-Diastolic,Volumes, Ventricular End-Systolic
D013599 Systole Period of contraction of the HEART, especially of the HEART VENTRICLES. Systolic Time Interval,Interval, Systolic Time,Intervals, Systolic Time,Systoles,Systolic Time Intervals,Time Interval, Systolic,Time Intervals, Systolic

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