[Blood transfusion in major orthopaedic surgery]. 2011

Øivind Jans, and Henrik Kehlet, and Pär I Johansson
Enhed for Kirurgisk Patofysiologi, 4074, Rigshospitalet, 2100 København Ø, Denmark. oeivind.jans@rh.regionh.dk

Hip and knee surgery is associated with a relatively large bleeding and a need for perioperative transfusion. Postoperative anaemia may delay recovery, but transfusion carries inherent risks. However, only few randomised controlled studies evaluating the effects of different transfusion triggers have been performed in orthopaedic surgery. The majority of these studies suffer from methodological weaknesses and have not been performed in a fast-track setting. Thus, large randomised studies evaluating a restrictive versus a liberal transfusion strategy in a procedure-specific setup are needed.

UI MeSH Term Description Entries
D001803 Blood Transfusion The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed) Blood Transfusions,Transfusion, Blood,Transfusions, Blood
D004434 Early Ambulation Procedure to accelerate the ability of a patient to walk or move about by reducing the time to AMBULATION. It is characterized by a shorter period of hospitalization or recumbency than is normally practiced. Ambulation, Early,Early Mobilization,Accelerated Ambulation,Ambulation, Accelerated,Mobilization, Early
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000740 Anemia A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN. Anemias
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D016063 Blood Loss, Surgical Loss of blood during a surgical procedure. Hemorrhage, Surgical,Surgical Blood Loss,Surgical Hemorrhage,Surgical Blood Losses,Surgical Hemorrhages
D017410 Practice Guidelines as Topic Works about directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery. Clinical Guidelines as Topic,Best Practices,Best Practice
D017707 Erythrocyte Transfusion The transfer of erythrocytes from a donor to a recipient or reinfusion to the donor. Red Blood Cell Transfusion,Red Blood Cell Transfusions,Transfusion, Red Blood Cell,Transfusions, Red Blood Cell,Erythrocyte Transfusions,Transfusion, Erythrocyte,Transfusions, Erythrocyte
D019106 Postoperative Hemorrhage Hemorrhage following any surgical procedure. It may be immediate or delayed and is not restricted to the surgical wound. Blood Loss, Postoperative,Hemorrhage, Postoperative,Hemorrhages, Postoperative,Postoperative Hemorrhages,Loss, Postoperative Blood,Postoperative Blood Loss
D019317 Evidence-Based Medicine An approach of practicing medicine with the goal to improve and evaluate patient care. It requires the judicious integration of best research evidence with the patient's values to make decisions about medical care. This method is to help physicians make proper diagnosis, devise best testing plan, choose best treatment and methods of disease prevention, as well as develop guidelines for large groups of patients with the same disease. (from JAMA 296 (9), 2006) Medicine, Evidence-Based,Evidence Based Medicine,Medicine, Evidence Based

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