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Atrial natriuretic peptide (ANP), a new cardiac hormone, has potent natriuretic, diuretic and vaso-relaxant properties in animals and humans. Plasma ANP levels increased in response to volume expansion, atrial distension or postural change. The present investigation was designed to examine the effect of labour on plasma ANP in normotensive pregnant women. The results show that plasma ANP in pregnant women (n = 9) increased significantly in active phase of first stage of labour from 19.5 +/- 4.6 pg/ml to 74.5 +/- 15.1 pg/ml. The magnitude of the increase in ANP levels in active phase varied among the patients. During and after delivery, plasma ANP decreased in all instances towards control level. The cause for the increase in plasma ANP levels in the active phase remains to be determined.
E F Wong, and
L W Koh, and
M H Huang, and
N L Wong
January 1989,
American journal of obstetrics and gynecology,
E F Wong, and
L W Koh, and
M H Huang, and
N L Wong
June 1988,
Journal of cardiothoracic anesthesia,
E F Wong, and
L W Koh, and
M H Huang, and
N L Wong
November 1987,
European journal of obstetrics, gynecology, and reproductive biology,
E F Wong, and
L W Koh, and
M H Huang, and
N L Wong
April 1987,
Lancet (London, England),
E F Wong, and
L W Koh, and
M H Huang, and
N L Wong
January 1998,
Journal of perinatal medicine,
E F Wong, and
L W Koh, and
M H Huang, and
N L Wong
March 1996,
Renal failure,
E F Wong, and
L W Koh, and
M H Huang, and
N L Wong
December 1987,
Clinical endocrinology,
E F Wong, and
L W Koh, and
M H Huang, and
N L Wong
December 1991,
Surgery,
E F Wong, and
L W Koh, and
M H Huang, and
N L Wong
January 1994,
Nephron,
E F Wong, and
L W Koh, and
M H Huang, and
N L Wong
June 1998,
Journal of maternal-fetal investigation : the official journal of French Society of Ultrasound in Medicine and Biology ... [et al.],
