The results of 27 percutaneous transluminal angioplasties (PTA) of the subclavian artery are reported in 25 patients. 13 patients complained of claudicatio brachii, 7 also demonstrated symptoms of vertebral-basilar insufficiency. In 5 cases this was the sole indication for PTA. 23 (85.2%) of 27 interventions were limited to the proximal section of the subclavian artery. In 22 (81%) the obstructions were localized on the left side. A technical success could be achieved in 24 (88.9%) of 27 interventions. The angiographic appearance of the homolateral vertebral arteries before and after PTA differed significantly. No PTA led to an occlusion of the previously patent vertebral artery. A retrograde flow was no longer seen after PTA. The haemodynamic significance was also demonstrated by the differences in brachial-occlusion pressures (mean 51 mmHg before, 7 mmHg after PTA). Complete or partial relief was achieved after technically successful PTA in 90% of patients with brachial symptoms and in 50% with vertebral-basilar insufficiency. Complications occurred in one (3.7%) of 27 procedures. Published data on PTA of the subclavian artery are discussed.