Seventy patients of schizophrenia were divided into two groups based on the presence or absence of substance abusing history in them. Two groups were compared on various socio-demographic and clinical variables. Thirty-eight (54.3%) patients could be diagnosed as having comorbid alcohol/substance abuse/dependence. Seventeen (24.3%) of them were poly-substance abusers. Comorbid substance abusers were predominantly represented by positive syndrome while non-abusers by negative syndrome. In contrast to the report by the most western researchers, most patients in the present study with a diagnosis of substance abusing schizophrenia were married. Similar study from a developing country is rare in the existing literature.