| D002478 |
Cells, Cultured |
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others. |
Cultured Cells,Cell, Cultured,Cultured Cell |
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| D004261 |
DNA Replication |
The process by which a DNA molecule is duplicated. |
Autonomous Replication,Replication, Autonomous,Autonomous Replications,DNA Replications,Replication, DNA,Replications, Autonomous,Replications, DNA |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D000071857 |
Tumor Suppressor p53-Binding Protein 1 |
A nuclear and cytoplasmic protein that associates with KINETOCHORES and contains a C-terminal TUDOR DOMAIN. It plays a critical role in the cellular response to DNA DAMAGE and localizes to DOUBLE-STRAND DNA BREAKS. It may also function in M PHASE CELL CYCLE CHECKPOINTS and as an enhancer of TUMOR SUPPRESSOR PROTEIN P53-mediated transcriptional activation. |
53BP1 Protein,TP53BP1 Protein,Tumor Protein p53-Binding Protein, 1,p202 Protein,Tumor Protein p53 Binding Protein, 1,Tumor Suppressor p53 Binding Protein 1 |
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| D014157 |
Transcription Factors |
Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process. |
Transcription Factor,Factor, Transcription,Factors, Transcription |
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| D014158 |
Transcription, Genetic |
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION. |
Genetic Transcription |
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| D016193 |
G1 Phase |
The period of the CELL CYCLE preceding DNA REPLICATION in S PHASE. Subphases of G1 include "competence" (to respond to growth factors), G1a (entry into G1), G1b (progression), and G1c (assembly). Progression through the G1 subphases is effected by limiting growth factors, nutrients, or inhibitors. |
First Gap Phase,G1a Phase,G1b Phase,Gap Phase 1,First Gap Phases,G1 Phases,G1a Phases,G1b Phases,Gap Phase, First,Gap Phases, First,Phase 1, Gap,Phase, First Gap,Phase, G1,Phase, G1a,Phase, G1b,Phases, First Gap,Phases, G1,Phases, G1a,Phases, G1b |
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| D047908 |
Intracellular Signaling Peptides and Proteins |
Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors. |
Intracellular Signaling Peptides,Intracellular Signaling Proteins,Peptides, Intracellular Signaling,Proteins, Intracellular Signaling,Signaling Peptides, Intracellular,Signaling Proteins, Intracellular |
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| D050811 |
Octamer Transcription Factor-1 |
A ubiquitously expressed octamer transcription factor that regulates GENETIC TRANSCRIPTION of SMALL NUCLEAR RNA; IMMUNOGLOBULIN GENES; and HISTONE H2B genes. |
Oct-1 Transcription Factor,Transcription Factor Oct-1,NFIII Transcription Factor,Nuclear Factor III,OTF-1 Transcription Factor,Octamer Transcription Factor 1,Octamer Transcription Factor OTF-1,Transcription Factor OTF-1,OTF 1 Transcription Factor,OTF-1, Transcription Factor,Oct 1 Transcription Factor,Oct-1, Transcription Factor,Octamer Transcription Factor OTF 1,Transcription Factor OTF 1,Transcription Factor Oct 1,Transcription Factor, NFIII,Transcription Factor, OTF-1,Transcription Factor, Oct-1,Transcription Factor-1, Octamer |
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