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Indolent systemic mastocytosis without skin involvement vs. isolated bone marrow mastocytosis. 2011

Luis Escribano, and Ivan Alvarez-Twose, and Andres Garcia-Montero, and Laura Sanchez-Muñoz, and Maria Jara-Acevedo, and Alberto Orfao

UI MeSH Term Description Entries
D008415 Mastocytosis A rare neoplastic disorder characterized by a clonal proliferation of MAST CELLS, associated with KIT-D816 mutations, and accompanied by aberrant mast cell activation. The abnormal increase of MAST CELLS may occur in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMA).
D001853 Bone Marrow The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells. Marrow,Red Marrow,Yellow Marrow,Marrow, Bone,Marrow, Red,Marrow, Yellow
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D034721 Mastocytosis, Systemic A group of disorders caused by the abnormal proliferation of MAST CELLS in a variety of extracutaneous tissues including bone marrow, liver, spleen, lymph nodes, and gastrointestinal tract. Systemic mastocytosis is commonly seen in adults. These diseases are categorized on the basis of clinical features, pathologic findings, and prognosis. Systemic Mast-Cell Disease,Aggressive Systemic Mastocytosis,Indolent Systemic Mastocytosis,Aggressive Systemic Mastocytoses,Indolent Systemic Mastocytoses,Mast-Cell Disease, Systemic,Mast-Cell Diseases, Systemic,Mastocytoses, Aggressive Systemic,Mastocytoses, Indolent Systemic,Mastocytoses, Systemic,Mastocytosis, Aggressive Systemic,Mastocytosis, Indolent Systemic,Systemic Mast Cell Disease,Systemic Mast-Cell Diseases,Systemic Mastocytoses,Systemic Mastocytoses, Aggressive,Systemic Mastocytoses, Indolent,Systemic Mastocytosis,Systemic Mastocytosis, Aggressive,Systemic Mastocytosis, Indolent

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