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The cell surface morphology of two cell lines--from the mink lung (Mv1Lu) and from the Kirsten sarcoma virus transformed derivate (Ki-Mv1Lu)--was studied by scanning electron microscopy. Marked differences are seen in cell morphology of these two lines at high cell densities. Mv1Lu cells at high densities had uniform flat polygonal shape with microvilli at their surface. A marked diversity in cell morphology was characteristic of Ki-Mv1Lu cells at comparable cell densities: variation in shape, in thickness degrees, and in the expression of cell surface ultrastructure (microvilli, blebs, filopodia). No dependence of Ki-Mv1Lu cell morphology from cell densities was observed. At low cell densities of Mv1Lu cells, cells with the morphology differing from the typical pattern of confluent Mv1Lu cells were seen. Morphological diversity of these cells was comparable with that of Ki-Mv1Lu cells. Nothing has been found in cell surface morphology that could be absolutely specific for transformed cells only.
E I Samil'chuk, and
V V Timanovskaia, and
G G Kukava
July 1982,
Tsitologiia,
E I Samil'chuk, and
V V Timanovskaia, and
G G Kukava
October 1989,
The Journal of antibiotics,
E I Samil'chuk, and
V V Timanovskaia, and
G G Kukava
August 1964,
Virology,
E I Samil'chuk, and
V V Timanovskaia, and
G G Kukava
September 1985,
Laboratory investigation; a journal of technical methods and pathology,
E I Samil'chuk, and
V V Timanovskaia, and
G G Kukava
January 1974,
Biochemical Society symposium,
E I Samil'chuk, and
V V Timanovskaia, and
G G Kukava
July 1984,
FEBS letters,
E I Samil'chuk, and
V V Timanovskaia, and
G G Kukava
January 1980,
Results and problems in cell differentiation,
E I Samil'chuk, and
V V Timanovskaia, and
G G Kukava
March 1973,
Experimental cell research,
E I Samil'chuk, and
V V Timanovskaia, and
G G Kukava
August 1963,
Journal of cellular and comparative physiology,
E I Samil'chuk, and
V V Timanovskaia, and
G G Kukava
January 1976,
The Journal of cell biology,
