Biomaterial Database

[AIDS in children based on autopsy data from the Kalmyk ASSR]. 1990

G G Vasil'eva, and A V Tsinzerling, and L A Kozhemiakin, and I G Bondarenko

6 cases of HIV infection were revealed by enzyme immunoassay and immunoblotting among 144 children who had died in Elista. Another 5 children might have had HIV-infection but laboratory analyses either were lacking or gave doubtful results. Laboratory results were negative in 133 children. Similar severe changes of the lymphoid system typical for immunodeficiency were found in all children. These changes in HIV infection were characterized by lymphogenic generalized RNA infection. Complications (secondary diseases) in the form of DNA-virus infections (cytomegalia and herpes simplex), pneumocystosis and other viral and bacterial processes were observed in children of all groups. The disease was found mainly in Kalmyks. Blood examination of healthy Kalmyks revealed some differences in the form of significant decrease of the lysosomal cationic proteins content and the peroxydase activity of neutrophil leucocytes as compared to the same indexes obtained in Leningrad. There was also a tendency to the decrease of T-lymphocyte content. The children dying from immunodeficiencies lived mainly along the litoral of an ancient sea.

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D008297	Male		Males
D009894	Opportunistic Infections	An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.	Infection, Opportunistic,Infections, Opportunistic,Opportunistic Infection
D012111	Residence Characteristics	Elements of residence that characterize a population. They are applicable in determining need for and utilization of health services.	Community,Domicile,Living Arrangements,Neighborhood,Place of Birth,Residential Selection,Arrangement, Living,Birth Place,Communities,Domiciles,Living Arrangement,Neighborhoods,Residence Characteristic
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000163	Acquired Immunodeficiency Syndrome	An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.	AIDS,Immunodeficiency Syndrome, Acquired,Immunologic Deficiency Syndrome, Acquired,Acquired Immune Deficiency Syndrome,Acquired Immuno-Deficiency Syndrome,Acquired Immuno Deficiency Syndrome,Acquired Immuno-Deficiency Syndromes,Acquired Immunodeficiency Syndromes,Immuno-Deficiency Syndrome, Acquired,Immuno-Deficiency Syndromes, Acquired,Immunodeficiency Syndromes, Acquired,Syndrome, Acquired Immuno-Deficiency,Syndrome, Acquired Immunodeficiency,Syndromes, Acquired Immuno-Deficiency,Syndromes, Acquired Immunodeficiency
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths