[The identification of Leishmania isolates obtained from patients and dogs with visceral leishmaniasis in the Turkmen SSR]. 1990

E V Lesnikova, and E A Sabitov, and M V Strelkova, and A V Shurkhal, and T A Rakitskaia

Using electrophoresis in polyacrylamide gel, 11 isolates have been detected by 8 enzymes (PGI, PGM, 6-PGD, MDG, G-6-PGD, ME, ALAT, ASAT) from patients with visceral leishmaniasis and dogs in the Turkmen SSR. The isolates were obtained from different areas of the republic varying in landscape and climatic conditions. The isolates were maintained by passages on golden hamsters. No long-lasting Leishmania culture has been obtained on the nutrition medium for any of the isolates. Parasite biomass was obtained by cultivation of spleen and liver suspensions on the nutrition medium. All the isolates were identified as Leishmania infantum, representing, however, independent zymodems. Isolates from human patients identified by PGI in the foci of the southeastern Kara Kum were distinct from those isolated from human patients in the foci of western Kopet-Dag. The isolates from 1-2-year-old children and an adult patient aged 31 in the same area were identical. The isolates from dogs were different from human ones in PGI and were not identical with Lem 78 marker isolated from dogs.

UI MeSH Term Description Entries
D007893 Leishmania donovani A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals and causes visceral leishmaniasis (LEISHMANIASIS, VISCERAL). The sandfly genera Phlebotomus and Lutzomyia are the vectors. Leishmania (Leishmania) donovani,Leishmania leishmania donovani,Leishmania donovanus,Leishmania leishmania donovanus,donovani, Leishmania leishmania,donovanus, Leishmania,donovanus, Leishmania leishmania,leishmania donovanus, Leishmania
D007898 Leishmaniasis, Visceral A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African. Black Fever,Kala-Azar,Fever, Black,Kala Azar,Visceral Leishmaniasis
D004197 Disease Reservoirs Animate or inanimate sources which normally harbor disease-causing organisms and thus serve as potential sources of disease outbreaks. Reservoirs are distinguished from vectors (DISEASE VECTORS) and carriers, which are agents of disease transmission rather than continuing sources of potential disease outbreaks. Humans may serve both as disease reservoirs and carriers. Disease Reservoir,Human Disease Reservoirs,Infectious Disease Reservoir,Reservoirs of Infection,Infectious Disease Reservoirs,Disease Reservoir, Human,Disease Reservoir, Infectious,Disease Reservoirs, Human,Human Disease Reservoir,Infection Reservoir,Infection Reservoirs,Reservoir, Disease,Reservoir, Infectious Disease,Reservoirs, Human Disease
D004283 Dog Diseases Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used. Canine Diseases,Canine Disease,Disease, Canine,Disease, Dog,Diseases, Canine,Diseases, Dog,Dog Disease
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D014423 Turkmenistan Turkmen S.S.R.,Turkmen SSR

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