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The ingestion of opsonized zymosan particles by neutrophil blood granulocytes and the chemiluminescence in samples of whole blood, induced by zymosan, Streptococcus mutans as well as phorbol myristate acetate, as a measure of the generation of reactive oxygene species were studied in patients with various forms of marginal periodontitis. Compared to a control group the phagocytic activity was found to be enhanced in progressive adult periodontitis and diminished in juvenile periodontitis whereas no differences to controls were found in chronic nonprogressive or postjuvenile periodontitis. With respect to the height of the chemiluminescence signals increased values were only measured in chronic nonprogressive periodontitis after stimulation by phorbol myristate acetate. The results indicate that impairment of blood granulocyte functions may be a pathogenetic factor for the development and the progression of marginal periodontitis.
P Brachmann, and
C Brandes, and
S Krause, and
E Michel, and
T Hoffmann, and
W Lösche, and
P Gängler
October 1987,
Minerva stomatologica,
P Brachmann, and
C Brandes, and
S Krause, and
E Michel, and
T Hoffmann, and
W Lösche, and
P Gängler
January 1986,
Vestnik dermatologii i venerologii,
P Brachmann, and
C Brandes, and
S Krause, and
E Michel, and
T Hoffmann, and
W Lösche, and
P Gängler
February 1985,
Vnitrni lekarstvi,
P Brachmann, and
C Brandes, and
S Krause, and
E Michel, and
T Hoffmann, and
W Lösche, and
P Gängler
January 1994,
Klinicheskaia khirurgiia,
P Brachmann, and
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S Krause, and
E Michel, and
T Hoffmann, and
W Lösche, and
P Gängler
October 1968,
Comptes rendus des seances de la Societe de biologie et de ses filiales,
P Brachmann, and
C Brandes, and
S Krause, and
E Michel, and
T Hoffmann, and
W Lösche, and
P Gängler
January 1980,
Journal of medicine,
P Brachmann, and
C Brandes, and
S Krause, and
E Michel, and
T Hoffmann, and
W Lösche, and
P Gängler
January 1992,
Folia biologica,
P Brachmann, and
C Brandes, and
S Krause, and
E Michel, and
T Hoffmann, and
W Lösche, and
P Gängler
October 1990,
Vrachebnoe delo,
P Brachmann, and
C Brandes, and
S Krause, and
E Michel, and
T Hoffmann, and
W Lösche, and
P Gängler
February 1991,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
P Brachmann, and
C Brandes, and
S Krause, and
E Michel, and
T Hoffmann, and
W Lösche, and
P Gängler
June 1992,
Likars'ka sprava,
