Endoscopic features of sessile serrated adenoma and other serrated colorectal polyps. 2011

Atsushi Yamada, and Kenji Notohara, and Ikuo Aoyama, and Masatsugu Miyoshi, and Shinichi Miyamoto, and Shigehiko Fujii, and Hiroshi Yamamoto
Department of Gastroenterology and Hepatology, Kyoto University Hospital, Kyoto, Japan. yatsushi@kuhp.kyoto-u.ac.jp

OBJECTIVE Sessile serrated adenoma is a subtype of serrated colorectal polyps that can potentially give rise to colorectal carcinoma. We aimed to characterize the endoscopic features of sessile serrated adenoma as compared to those of other subtypes of serrated colorectal polyps. METHODS A total of 202 serrated colorectal polyps were retrospectively collected and pathologically subclassified as sessile serrated adenoma, hyperplastic polyp, or traditional serrated adenoma. The patients' demographics and endoscopic findings were reviewed, and comparisons were made between groups. RESULTS We found 57 sessile serrated adenomas, 104 hyperplastic polyps, and 41 traditional serrated adenomas. Sessile serrated adenomas were larger in size, and they had more granular or nodular surface and more irregular or vague margin than hyperplastic polyps; however, these two subgroups were similar in terms of their sessile configuration and white coloring. Sessile serrated adenomas could be distinguished from traditional serrated adenomas based on the pedunculated configuration and red coloring unique to the traditional serrated adenomas. Nine sessile serrated adenomas were of note due to coverage with abundant mucus, which was rarely seen in other subgroups. CONCLUSIONS We characterize the endoscopic features of sessile serrated adenoma as compared to those of hyperplastic polyp and traditional serrated adenoma.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D003111 Colonic Polyps Discrete tissue masses that protrude into the lumen of the COLON. These POLYPS are connected to the wall of the colon either by a stalk, pedunculus, or by a broad base. Colonic Polyp,Polyp, Colonic,Polyps, Colonic
D003113 Colonoscopy Endoscopic examination, therapy or surgery of the luminal surface of the colon. Colonoscopic Surgical Procedures,Surgical Procedures, Colonoscopic,Colonoscopic Surgery,Surgery, Colonoscopic,Colonoscopic Surgeries,Colonoscopic Surgical Procedure,Colonoscopies,Procedure, Colonoscopic Surgical,Procedures, Colonoscopic Surgical,Surgeries, Colonoscopic,Surgical Procedure, Colonoscopic
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000236 Adenoma A benign epithelial tumor with a glandular organization. Adenoma, Basal Cell,Adenoma, Follicular,Adenoma, Microcystic,Adenoma, Monomorphic,Adenoma, Papillary,Adenoma, Trabecular,Adenomas,Adenomas, Basal Cell,Adenomas, Follicular,Adenomas, Microcystic,Adenomas, Monomorphic,Adenomas, Papillary,Adenomas, Trabecular,Basal Cell Adenoma,Basal Cell Adenomas,Follicular Adenoma,Follicular Adenomas,Microcystic Adenoma,Microcystic Adenomas,Monomorphic Adenoma,Monomorphic Adenomas,Papillary Adenoma,Papillary Adenomas,Trabecular Adenoma,Trabecular Adenomas
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D013194 Staining and Labeling The marking of biological material with a dye or other reagent for the purpose of identifying and quantitating components of tissues, cells or their extracts. Histological Labeling,Staining,Histological Labelings,Labeling and Staining,Labeling, Histological,Labelings, Histological,Stainings

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