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A case is presented in which sensory ataxic neuronopathy developed after serologically proven infection with Rickettsia conorii and continued to be progressive after appropriate antibiotic treatment. Electrophysiological studies showed decreasing sensory nerve conduction velocities ending with the absence of sensory nerve action potentials as well as peripheral and cortical somatosensory evoked potentials. Histological studies revealed a profound loss of myelinated fibres due to primarily axonal degeneration. The clinical course and the electrophysiological and histological findings suggest primary involvement of the dorsal root ganglion. Peripheral neuropathy due to infection with R. conorii is rare and usually of the mixed motor and sensory type. We believe this to be the first report of sensory ataxic neuronopathy associated with R. conorii infection.
H B Verbiest, and
T C van Woerkom, and
A M Dumas, and
G T Bots, and
L J Endtz
January 2019,
Frontiers in neurology,
H B Verbiest, and
T C van Woerkom, and
A M Dumas, and
G T Bots, and
L J Endtz
January 1988,
Neurologia (Barcelona, Spain),
H B Verbiest, and
T C van Woerkom, and
A M Dumas, and
G T Bots, and
L J Endtz
June 2024,
Internal medicine (Tokyo, Japan),
H B Verbiest, and
T C van Woerkom, and
A M Dumas, and
G T Bots, and
L J Endtz
November 2014,
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology,
H B Verbiest, and
T C van Woerkom, and
A M Dumas, and
G T Bots, and
L J Endtz
April 1992,
Muscle & nerve,
H B Verbiest, and
T C van Woerkom, and
A M Dumas, and
G T Bots, and
L J Endtz
January 1994,
Presse medicale (Paris, France : 1983),
H B Verbiest, and
T C van Woerkom, and
A M Dumas, and
G T Bots, and
L J Endtz
June 2001,
The Israel Medical Association journal : IMAJ,
H B Verbiest, and
T C van Woerkom, and
A M Dumas, and
G T Bots, and
L J Endtz
December 2009,
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases,
H B Verbiest, and
T C van Woerkom, and
A M Dumas, and
G T Bots, and
L J Endtz
February 2019,
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia,
H B Verbiest, and
T C van Woerkom, and
A M Dumas, and
G T Bots, and
L J Endtz
January 2014,
Rinsho shinkeigaku = Clinical neurology,
