Approaches to tyrosine-linked peptidomimetic prodrugs of (S)-HPMP-based acyclic nucleoside phosphonates. 2011

Valeria M Zakharova, and Ivan S Krylov, and Michaela Serpi, and Boris A Kashemirov, and Charles E McKenna
Department of Chemistry, University of Southern California, Los Angeles, CA 90089-0744, USA.

Synthetic approaches to a new class of tyrosine-linked prodrugs of two 3-hydroxy-2-(phosphonomethoxypropyl) (HPMP) nucleotide analogues ((S)-HPMPC and (S)-HPMPA) are outlined.

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