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BACKGROUND Radiation induced haemorrhagic proctitis is a well recognized complication of pelvic radiotherapy and its treatment is quite challenging. OBJECTIVE To evaluate the efficacy of local instillation of 4% formalin in the management of uncontrolled radiation induced haemorrhagic proctitis. METHODS This prospective study included twenty-three patients who underwent formalin instillation. We documented the control of the symptoms, assessed the outcome of the treatment, presence of complications & long term results. RESULTS All patients were followed for a median of 13 months. In 15 patients, the bleeding stopped after a single treatment and in 6 after a second session. Only two patients required formalin instillation for the third time. During the follow-up period all patients were reviewed systemically with reference to the pretreatment complaints. No recurrent rectal bleeding occurred, bowel frequency was decreased and no further blood transfusion was required. CONCLUSIONS Local instillation of 4% formalin is an effective treatment for uncontrolled radiation induced haemorrhagic proctitis.
Gautam Chattopadhyay, and
Dipankar Ray, and
Saurav Chakravartty, and
Subhayan Mandal
May 2012,
International journal of colorectal disease,
Gautam Chattopadhyay, and
Dipankar Ray, and
Saurav Chakravartty, and
Subhayan Mandal
January 2002,
Digestive surgery,
Gautam Chattopadhyay, and
Dipankar Ray, and
Saurav Chakravartty, and
Subhayan Mandal
May 2002,
Journal of surgical oncology,
Gautam Chattopadhyay, and
Dipankar Ray, and
Saurav Chakravartty, and
Subhayan Mandal
June 2005,
Surgical innovation,
Gautam Chattopadhyay, and
Dipankar Ray, and
Saurav Chakravartty, and
Subhayan Mandal
July 2002,
Annals of the Royal College of Surgeons of England,
Gautam Chattopadhyay, and
Dipankar Ray, and
Saurav Chakravartty, and
Subhayan Mandal
May 2006,
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland,
Gautam Chattopadhyay, and
Dipankar Ray, and
Saurav Chakravartty, and
Subhayan Mandal
February 1995,
The British journal of surgery,
Gautam Chattopadhyay, and
Dipankar Ray, and
Saurav Chakravartty, and
Subhayan Mandal
July 2011,
BMJ case reports,
Gautam Chattopadhyay, and
Dipankar Ray, and
Saurav Chakravartty, and
Subhayan Mandal
February 1996,
Diseases of the colon and rectum,
Gautam Chattopadhyay, and
Dipankar Ray, and
Saurav Chakravartty, and
Subhayan Mandal
March 2007,
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland,
