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2'-Methyl-pyrazolo[4',3':16,17]androst-5-en-3β-ol. 2009

Hu-Ling Zheng, and Peng Xia, and Ying Chen
Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 138 Yixueyuan Road Shanghai 200032, People's Republic of China.

In the title compound, C(21)H(30)N(2)O, there are five fused rings. The A and C rings adopt chair conformations, ring B adopts an 8β,9α-half-chair conformation and ring D adopts a 14α-envelope conformation. The pyrazole ring is planar. Inter-molecular O-H⋯N hydrogen bonds [H⋯N = 1.88 (5) Å] help to stabilize the crystal structure. The absolute structure was deduced from those of the starting materials.

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