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Regional intraarterial infusion chemotherapy without laparotomy for hepatic metastases of pancreatic-cancer. 1992

A Nakaizumi, and M Tatsuta, and H Uehara, and T Kitamura, and S Okuda, and H Ohigashi, and O Ishikawa, and M Fujita, and Y Matayoshi
CTR ADULT DIS,DEPT RADIAT THERAPY,HIGASHINARI KU,OSAKA 537,JAPAN. CTR ADULT DIS,DEPT RADIOL,HIGASHINARI KU,OSAKA 537,JAPAN. CTR ADULT DIS,DEPT ULTRASONOG,HIGASHINARI KU,OSAKA 537,JAPAN. CTR ADULT DIS,DEPT GASTROENTEROL,HIGASHINARI KU,OSAKA 537,JAPAN. CTR ADULT DIS,DEPT SURG,HIGASHINARI KU,OSAKA 537,JAPAN.

The therapeutic effectiveness of regional infusional chemotherapy for treatment of hepatic metastases of pancreatic cancers was compared with systemic chemotherapy. Studies were made on 17 patients with unresectable pancreatic cancer with hepatic metastases. Regional infusion chemotherapy was performed after the insertion of an angiocatheter into the hepatic artery without laparotomy. This treatment significantly increased the rate of the partial response (40%) of the hepatic metastases, prolonged the survival and reduced the duration of the hospital stay. As hepatic infusion chemotherapy without laparotomy is also simple and inexpensive, it should be useful for treatment of hepatic metastases of pancreatic cancer.

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