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10B concentration evaluation in autoradiography images by optical density measurements. 2011
Centro Atómico Constituyentes (CAC), Comisión Nacional de Energía Atómica (CNEA), San Martín, Buenos Aires, Argentina. portu@cnea.gov
The quantification and analysis of the tracks forming the autoradiography image of a tissue section is essential for the measurement of particle emitter concentration and distribution (e.g. (10)B) in the sample. Conventional counting techniques cannot be used when track density is high because of track overlapping. A densitometry supported by image analysis method suitable for these cases has been developed. Optical density measurements obtained for boron solutions of known concentrations showed a linear behavior in the range of concentrations under consideration.
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