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Two police officers developed asthma like illness after a single but prolonged exposure to toluene diisocyanate (TDI) by being in the immediate vicinity of a tank car that had overturned on a highway. One officer experienced upper and lower respiratory tract symptoms with chest tightness about 4.5 hours after initial exposure. Shortness of breath, cough, and wheezing were noted the following day. The other experienced symptoms immediately on exposure, developed shortness of breath 20 minutes later, and presented with wheezing four hours after that. Follow up examinations over seven years showed persistence of respiratory symptoms and continuation of airway hyperreactivity requiring treatment.
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K G Nelsen, and
A Fischbein
July 1995,
Nihon Kyobu Shikkan Gakkai zasshi,
J C Luo, and
K G Nelsen, and
A Fischbein
January 2010,
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J C Luo, and
K G Nelsen, and
A Fischbein
April 2001,
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J C Luo, and
K G Nelsen, and
A Fischbein
August 2007,
Scandinavian journal of work, environment & health,
J C Luo, and
K G Nelsen, and
A Fischbein
January 1997,
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J C Luo, and
K G Nelsen, and
A Fischbein
October 2004,
Scandinavian journal of work, environment & health,
J C Luo, and
K G Nelsen, and
A Fischbein
December 2002,
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J C Luo, and
K G Nelsen, and
A Fischbein
November 1977,
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J C Luo, and
K G Nelsen, and
A Fischbein
July 1986,
The American review of respiratory disease,
J C Luo, and
K G Nelsen, and
A Fischbein
January 1993,
International archives of occupational and environmental health,
