Cultivation of foot-and-mouth disease virus in BHK21 cells grown in microcarrier culture system. 1990

M Ferrari, and M N Losio, and G L Gualandi, and M Bugnetti
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia, Brescia, Italy.

When BHK21 cells were grown according to the microcarrier's system, they reached the highest concentration in 72 hrs. The infectivity of Foot-and-Mouth Disease (FMD) virus in BHK21 microcarrier culture increased 10 times compared with the conventional monolayer culture in rolling bottles.

UI MeSH Term Description Entries
D007700 Kinetics The rate dynamics in chemical or physical systems.
D002460 Cell Line Established cell cultures that have the potential to propagate indefinitely. Cell Lines,Line, Cell,Lines, Cell
D005537 Aphthovirus A genus of the family PICORNAVIRIDAE infecting mainly cloven-hoofed animals. They cause vesicular lesions and upper respiratory tract infections. FOOT AND MOUTH DISEASE VIRUS is the type species. Equine rhinitis A virus,Equine rhinovirus 1,Aphthoviruses
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D014776 Virus Cultivation Process of growing viruses in live animals, plants, or cultured cells. Viral Cultivation,Cultivation, Viral,Cultivation, Virus,Cultivations, Viral,Cultivations, Virus,Viral Cultivations,Virus Cultivations

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