Biomaterial Database

Enzymes of phosphoinositide synthesis in secretory vesicles destined for the plasma membrane in Saccharomyces cerevisiae. 1990

A J Kinney, and G M Carman

Department of Food Science, Cook College, Rutgers University, New Brunswick, New Jersey 08903.

CDP-diacylglycerol synthase, phosphatidylinositol synthase, and phosphatidylinositol kinase activities were associated with post-Golgi apparatus secretory vesicles destined for the plasma membrane of Saccharomyces cerevisiae. These results suggest that the plasma membrane is capable of synthesizing both CDP-diacylglycerol and phosphatidylinositol as well as phosphorylating phosphatidylinositol.

UI	MeSH Term	Description	Entries
D008861	Microsomes	Artifactual vesicles formed from the endoplasmic reticulum when cells are disrupted. They are isolated by differential centrifugation and are composed of three structural features: rough vesicles, smooth vesicles, and ribosomes. Numerous enzyme activities are associated with the microsomal fraction. (Glick, Glossary of Biochemistry and Molecular Biology, 1990; from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)	Microsome
D008970	Molecular Weight	The sum of the weight of all the atoms in a molecule.	Molecular Weights,Weight, Molecular,Weights, Molecular
D009713	Nucleotidyltransferases	A class of enzymes that transfers nucleotidyl residues. EC 2.7.7.	Nucleotidyltransferase
D010716	Phosphatidylinositols	Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to the hexahydroxy alcohol, myo-inositol. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid, myo-inositol, and 2 moles of fatty acids.	Inositide Phospholipid,Inositol Phosphoglyceride,Inositol Phosphoglycerides,Inositol Phospholipid,Phosphoinositide,Phosphoinositides,PtdIns,Inositide Phospholipids,Inositol Phospholipids,Phosphatidyl Inositol,Phosphatidylinositol,Inositol, Phosphatidyl,Phosphoglyceride, Inositol,Phosphoglycerides, Inositol,Phospholipid, Inositide,Phospholipid, Inositol,Phospholipids, Inositide,Phospholipids, Inositol
D010770	Phosphotransferases	A rather large group of enzymes comprising not only those transferring phosphate but also diphosphate, nucleotidyl residues, and others. These have also been subdivided according to the acceptor group. (From Enzyme Nomenclature, 1992) EC 2.7.	Kinases,Phosphotransferase,Phosphotransferases, ATP,Transphosphorylase,Transphosphorylases,Kinase,ATP Phosphotransferases
D002462	Cell Membrane	The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.	Plasma Membrane,Cytoplasmic Membrane,Cell Membranes,Cytoplasmic Membranes,Membrane, Cell,Membrane, Cytoplasmic,Membrane, Plasma,Membranes, Cell,Membranes, Cytoplasmic,Membranes, Plasma,Plasma Membranes
D003594	Cytoplasmic Granules	Condensed areas of cellular material that may be bounded by a membrane.	Cytoplasmic Granule,Granule, Cytoplasmic,Granules, Cytoplasmic
D012441	Saccharomyces cerevisiae	A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.	Baker's Yeast,Brewer's Yeast,Candida robusta,S. cerevisiae,Saccharomyces capensis,Saccharomyces italicus,Saccharomyces oviformis,Saccharomyces uvarum var. melibiosus,Yeast, Baker's,Yeast, Brewer's,Baker Yeast,S cerevisiae,Baker's Yeasts,Yeast, Baker
D046911	Macromolecular Substances	Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure.	Macromolecular Complexes,Macromolecular Compounds,Macromolecular Compounds and Complexes,Complexes, Macromolecular,Compounds, Macromolecular,Substances, Macromolecular
D051607	CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase	An enzyme that catalyzes the formation of PHOSPHATIDYLINOSITOL and CMP from CDP-DIACYLGLYCEROL and MYOINOSITOL.	CDP-1,2-Diacyl-sn-Glycerol-Myoinositol 3-Phosphatidyltransferase,CDP-DG Inositol Transferase,CDP-Diacylglycerol-Myo-Inositol 3-Phosphatidyltransferase,CDP-Diglyceride-Inositol Transferase,CDP-Diglyceride-Inositoltransferase,CDPdiacylglycerol-Inositol 3-Phosphatidyltransferase,CDPdiglyceride-Inositol Phosphatidyltransferase,Cytidine 5'-Diphosphate 1,2-Diacyl-sn-Glycerol - Inositol Transferase,Inositol Phosphatidyltransferase,Phosphatidylinositol Synthase,3-Phosphatidyltransferase, CDP-1,2-Diacyl-sn-Glycerol-Myoinositol,3-Phosphatidyltransferase, CDP-Diacylglycerol-Inositol,3-Phosphatidyltransferase, CDP-Diacylglycerol-Myo-Inositol,3-Phosphatidyltransferase, CDPdiacylglycerol-Inositol,CDP 1,2 Diacyl sn Glycerol Myoinositol 3 Phosphatidyltransferase,CDP DG Inositol Transferase,CDP Diacylglycerol Inositol 3 Phosphatidyltransferase,CDP Diacylglycerol Myo Inositol 3 Phosphatidyltransferase,CDP Diglyceride Inositol Transferase,CDP Diglyceride Inositoltransferase,CDPdiacylglycerol Inositol 3 Phosphatidyltransferase,CDPdiglyceride Inositol Phosphatidyltransferase,Cytidine 5' Diphosphate 1,2 Diacyl sn Glycerol Inositol Transferase,Phosphatidyltransferase, CDPdiglyceride-Inositol,Phosphatidyltransferase, Inositol