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The effect of vitamin A-deficiency on jejunal Paneth cells in rats was investigated. Crystalloid particles were observed in secretion granules of Paneth cells from 6 out of 8 rats with vitamin A-deficiency. The particles were similar to those found in Paneth cells under other experimental conditions. Using an immuno-electron-microscopic technique we demonstrated a clear lysozyme immunoreactivity of these particles. In 2 vitamin A-deficient rats tubular structures have been detected in addition to the crystalloid particles. Crystalloid particles or tubular structures were not detectable in a control group of 8 vitamin A-supplemented rats. The morphological alterations of Paneth cells may be correlated to an impaired local immunity of the intestine during vitamin A-deficiency.
M J Koch, and
H K Biesalski, and
E Stofft, and
H Weiser, and
H E Gabbert, and
H P Dienes, and
B Schulz-Dobrick, and
K H Bässler
September 1990,
Histopathology,
M J Koch, and
H K Biesalski, and
E Stofft, and
H Weiser, and
H E Gabbert, and
H P Dienes, and
B Schulz-Dobrick, and
K H Bässler
January 1990,
Histopathology,
M J Koch, and
H K Biesalski, and
E Stofft, and
H Weiser, and
H E Gabbert, and
H P Dienes, and
B Schulz-Dobrick, and
K H Bässler
January 2018,
Autophagy,
M J Koch, and
H K Biesalski, and
E Stofft, and
H Weiser, and
H E Gabbert, and
H P Dienes, and
B Schulz-Dobrick, and
K H Bässler
January 1947,
Le Sang,
M J Koch, and
H K Biesalski, and
E Stofft, and
H Weiser, and
H E Gabbert, and
H P Dienes, and
B Schulz-Dobrick, and
K H Bässler
March 1981,
Acta pathologica et microbiologica Scandinavica. Section A, Pathology,
M J Koch, and
H K Biesalski, and
E Stofft, and
H Weiser, and
H E Gabbert, and
H P Dienes, and
B Schulz-Dobrick, and
K H Bässler
January 1989,
Acta anatomica,
M J Koch, and
H K Biesalski, and
E Stofft, and
H Weiser, and
H E Gabbert, and
H P Dienes, and
B Schulz-Dobrick, and
K H Bässler
January 1988,
Journal of submicroscopic cytology and pathology,
M J Koch, and
H K Biesalski, and
E Stofft, and
H Weiser, and
H E Gabbert, and
H P Dienes, and
B Schulz-Dobrick, and
K H Bässler
January 1972,
Beitrage zur Pathologie,
M J Koch, and
H K Biesalski, and
E Stofft, and
H Weiser, and
H E Gabbert, and
H P Dienes, and
B Schulz-Dobrick, and
K H Bässler
September 2015,
Nature immunology,
M J Koch, and
H K Biesalski, and
E Stofft, and
H Weiser, and
H E Gabbert, and
H P Dienes, and
B Schulz-Dobrick, and
K H Bässler
January 1972,
Comptes rendus des seances de la Societe de biologie et de ses filiales,
