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The temperature-regulated expression of capsular group II polysaccharides of Escherichia coli (B. Jann and K. Jann, (1990) Curr. Top. Microbiol. Immunol. 150: 19-42) depends on an elevated concentration of CMP-KDO, as evidenced by an increased activity of CMP-KDO synthetase. The increase in activity of CMP-KDO synthetase is observed only in cytoplasmic fractions of bacteria which had been grown at 37 degrees C but not after growth at 18 degrees C. The activity of CMP-KDO synthetase thus parallels the activity of the (membrane-associated) system synthesizing capsules of group II in E. coli. No such dependence of capsule expression on CMP-KDO was observed with E. coli with capsules of group I. A number of E. coli strains with capsular polysaccharides, which on the basis of genetic determination and chemical characteristics are considered as group II capsules, show no temperature regulation of their capsules and do not depend on an elevated CMP-KDO concentration for capsule expression. The capsular polysaccharides of these E. coli strains, which possibly represent a new group of E. coli capsules are tentatively classified as group I/II.
A Finke, and
B Jann, and
K Jann
January 1995,
FEMS microbiology letters,
A Finke, and
B Jann, and
K Jann
March 1995,
Bioorganic & medicinal chemistry,
A Finke, and
B Jann, and
K Jann
December 1986,
The Journal of biological chemistry,
A Finke, and
B Jann, and
K Jann
January 2008,
Advances in applied microbiology,
A Finke, and
B Jann, and
K Jann
April 2006,
Natural product research,
A Finke, and
B Jann, and
K Jann
May 1990,
BioTechniques,
A Finke, and
B Jann, and
K Jann
January 1982,
Methods in enzymology,
A Finke, and
B Jann, and
K Jann
October 2000,
Trends in genetics : TIG,
A Finke, and
B Jann, and
K Jann
March 1987,
Biochemical and biophysical research communications,
A Finke, and
B Jann, and
K Jann
January 2006,
Annual review of biochemistry,
