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In summary, 1.7 years after transplantation, bortezomib rescue has been durably effective in salvaging our patient with refractory antibody mediated rejection. The only price has been persistently high levels of BK viruria. The presence of ongoing and even recurrent donor specific antibody has made it difficult to reduce immunosuppression further, and the concern that the high levels of BK viruria will eventually progress to viremia and nephropathy necessitates continued therapy with very low dose cidofovir and leflunomide. The absence of C1q binding DSA with stable renal function may provide some reserved optimism that the DSA that is detectable by convention Luminex assay may have reduced pathological implications. However, more data and prolonged follow-up are needed to determine whether or not non-complement binding DSA has an adverse pathological role.
R Shapiro, and
J Lunz, and
A Zeevi, and
A Basu, and
M Mapara, and
P Randhawa, and
H P Tan, and
V Sharma, and
A Humar
January 2009,
Clinical transplants,
R Shapiro, and
J Lunz, and
A Zeevi, and
A Basu, and
M Mapara, and
P Randhawa, and
H P Tan, and
V Sharma, and
A Humar
October 2019,
Transplantation direct,
R Shapiro, and
J Lunz, and
A Zeevi, and
A Basu, and
M Mapara, and
P Randhawa, and
H P Tan, and
V Sharma, and
A Humar
January 2010,
Clinical transplants,
R Shapiro, and
J Lunz, and
A Zeevi, and
A Basu, and
M Mapara, and
P Randhawa, and
H P Tan, and
V Sharma, and
A Humar
December 2008,
Transplantation,
R Shapiro, and
J Lunz, and
A Zeevi, and
A Basu, and
M Mapara, and
P Randhawa, and
H P Tan, and
V Sharma, and
A Humar
November 2016,
Transplantation proceedings,
R Shapiro, and
J Lunz, and
A Zeevi, and
A Basu, and
M Mapara, and
P Randhawa, and
H P Tan, and
V Sharma, and
A Humar
March 2012,
Clinical nephrology,
R Shapiro, and
J Lunz, and
A Zeevi, and
A Basu, and
M Mapara, and
P Randhawa, and
H P Tan, and
V Sharma, and
A Humar
January 2010,
Clinical transplants,
R Shapiro, and
J Lunz, and
A Zeevi, and
A Basu, and
M Mapara, and
P Randhawa, and
H P Tan, and
V Sharma, and
A Humar
December 2013,
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation,
R Shapiro, and
J Lunz, and
A Zeevi, and
A Basu, and
M Mapara, and
P Randhawa, and
H P Tan, and
V Sharma, and
A Humar
December 2018,
HLA,
R Shapiro, and
J Lunz, and
A Zeevi, and
A Basu, and
M Mapara, and
P Randhawa, and
H P Tan, and
V Sharma, and
A Humar
September 2012,
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons,
