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Hypertrophic osteoarthropathy (HOA) is the classical neoplastic disease in rheumatology characterized by a combination of digital clubbing, joint and bone pain, and proliferative periostitis. This combination of symptoms should initiate an intensive search for an underlying malignant disease usually of thoracic organs. Here we report the case of a patient with HOA and neuroendocrine carcinoma of the esophagus. Other non-malignant disorders of the lungs, heart and other organs should be considered in the differential diagnosis. In addition, rare cases of a primary hereditary form of HOA exist and the genetic background has recently been discovered. Thus, new insights into the pathophysiology have improved diagnostic and therapeutic options for this disorder.
B Manger, and
A Lindner, and
K Manger, and
J Wacker, and
G Schett
January 1970,
Annali italiani di chirurgia,
B Manger, and
A Lindner, and
K Manger, and
J Wacker, and
G Schett
January 2005,
International journal of dermatology,
B Manger, and
A Lindner, and
K Manger, and
J Wacker, and
G Schett
January 1972,
Minerva ortopedica,
B Manger, and
A Lindner, and
K Manger, and
J Wacker, and
G Schett
December 1956,
Das Deutsche Gesundheitswesen,
B Manger, and
A Lindner, and
K Manger, and
J Wacker, and
G Schett
January 1960,
Acta tuberculosea et pneumologica Belgica,
B Manger, and
A Lindner, and
K Manger, and
J Wacker, and
G Schett
June 1962,
Klinicheskaia meditsina,
B Manger, and
A Lindner, and
K Manger, and
J Wacker, and
G Schett
January 1964,
Guy's Hospital reports,
B Manger, and
A Lindner, and
K Manger, and
J Wacker, and
G Schett
December 1949,
Prensa medica argentina,
B Manger, and
A Lindner, and
K Manger, and
J Wacker, and
G Schett
January 1994,
Rontgenpraxis; Zeitschrift fur radiologische Technik,
B Manger, and
A Lindner, and
K Manger, and
J Wacker, and
G Schett
August 1958,
Arztliche Wochenschrift,
