4,5-Bis(4-fluoro-phen-yl)-5-hy-droxy-3-(2-methyl-propano-yl)-1-phenyl-pyrrolidin-2-one. 2011

Jian-Ying Huang, and Fengyan Zhou

The title compound, C(26)H(23)F(2)NO(3), was synthesized by the reaction of 2-(4-fluoro-benzyl-idene)-4-methyl-3-oxo-N-phenyl-penta-namide and 4-fluoro-benzaldehyde. The dihedral angles between the mean plane through the pyrrolidine ring (nearly planar; maximum deviation of 0.145 Å for the C atom bearing the hydroxy group) with the phenyl and benzene rings are 37.22 (7), 51.88 (7) and 87.64 (9)°, respectively. The pyyolidine ring is near coplaner, with max offset of 0.145 A for C19 atom.\uff09 In the crystal, mol-ecules are linked by pairs of O-H⋯O hydrogen bonds into inversion dimers, which are further assembled into chains parallel to the b axis by weak C-H⋯O hydrogen bonds.

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