Biomaterial Database

Monocular deprivation and the signal transmission by X- and Y-neurons of the cat lateral geniculate nucleus. 1979

U T Eysel, and O J Grüsser, and K P Hoffmann

1. In adult cats deprived monocularly from the second week of life, single neurons were recorded from the optic tract (OT), the lateral geniculate body (pars dorsalis, LGN) and the optic radiation (OR). The neurons were classified according to their visual response properties (Y/X) or their latencies to OT electrical stimulation (class I/II). 2. A close positive correlation (greater than 95%) was found between the visual classification and the latency classification (Y = I, X = II). 3. The relative frequency of class I/Y-neurons was reduced in the group of pattern-deprived LGN neurons, but normal in the pattern-deprived OR neurons. 4. The ratio of the r1 and r2 wave amplitude of the OR-evoked potentials elicited by electrical stimulation of the normal or the deprived eye optic nerve was not affected by pattern deprivation. 5. The activity pattern of neurons recorded from the LGN or the OR did not differ in normal and pattern-deprived neurons belonging to the same class (on-center/off-center; Y/X). The same was true for the neuronal responses to electrical stimulation of the OT at different stimulus frequencies (1-200 stimuli/s). 6. The average maintained activity of pattern-deprived OT or OR neurons recorded while the eyelids of the deprived eye were still closed was either equal to or even somewhat higher than the average activity of the corresponding normal neurons. This was true when the patterned stimuli were presented stationary or were moved at random within the visual field simulating the effect of eye and head movements. The pattern deprivation effects found morphologically and physiologically in the visual cortex are, therefore, not induced by a diminished average activity of the input neurons from the deprived eye.

UI	MeSH Term	Description	Entries
D009435	Synaptic Transmission	The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.	Neural Transmission,Neurotransmission,Transmission, Neural,Transmission, Synaptic
D009474	Neurons	The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.	Nerve Cells,Cell, Nerve,Cells, Nerve,Nerve Cell,Neuron
D009900	Optic Nerve	The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.	Cranial Nerve II,Second Cranial Nerve,Nervus Opticus,Cranial Nerve, Second,Cranial Nerves, Second,Nerve, Optic,Nerve, Second Cranial,Nerves, Optic,Nerves, Second Cranial,Optic Nerves,Second Cranial Nerves
D010364	Pattern Recognition, Visual	Mental process to visually perceive a critical number of facts (the pattern), such as characters, shapes, displays, or designs.	Recognition, Visual Pattern,Visual Pattern Recognition
D010775	Photic Stimulation	Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity.	Stimulation, Photic,Visual Stimulation,Photic Stimulations,Stimulation, Visual,Stimulations, Photic,Stimulations, Visual,Visual Stimulations
D011930	Reaction Time	The time from the onset of a stimulus until a response is observed.	Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D012160	Retina	The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.	Ora Serrata
D002415	Cats	The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)	Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D004292	Dominance, Cerebral	Dominance of one cerebral hemisphere over the other in cerebral functions.	Cerebral Dominance,Hemispheric Specialization,Dominances, Cerebral,Specialization, Hemispheric
D004558	Electric Stimulation	Use of electric potential or currents to elicit biological responses.	Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical