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Twenty four patients with hepatocellular carcinoma who refused surgery or had unresectable tumor ranging 2.5 to 8.0 cm in size were treated with intrahepatic arterial injection of iodine-131-labeled iodized oil (I-131 Lipodol) in an attempt to achieve internal radiation of tumor. 555-2,220 MBq in 3-8 ml of I-131 Lipiodol was injected into the hepatic artery or proximal to the tumor feeding vessel depending on the tumor size. Tumor size reduction was observed in 88.9% of tumor smaller than 4.0 cm in diameter, 65.5% between 4.1 to 6.0 cm, and 25.0% of larger than 6.1cm, respectively. The tumor size reduction was corresponded to the gradual drop of serum AFP levels, decreased uptake on gallium-67 scintigraphy, and devascularization on follow-up angiography. Tumors having significant A-V shunts revealed further tumor growth. Adverse reactions from the treatment include fever, mild abdominal pain, nausea and elevation of transaminases. These have been mild and well-tolerated by the patients. This method was able to provide long term local control without complications related to thyroid, lung, GI tract and bone marrow.
H S Yoo, and
J H Suh, and
J T Lee, and
K W Kim, and
D I Kim, and
B S Kim, and
H J Choi, and
K S Lee
February 2000,
Cancer biotherapy & radiopharmaceuticals,
H S Yoo, and
J H Suh, and
J T Lee, and
K W Kim, and
D I Kim, and
B S Kim, and
H J Choi, and
K S Lee
June 2014,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
H S Yoo, and
J H Suh, and
J T Lee, and
K W Kim, and
D I Kim, and
B S Kim, and
H J Choi, and
K S Lee
January 2007,
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology,
H S Yoo, and
J H Suh, and
J T Lee, and
K W Kim, and
D I Kim, and
B S Kim, and
H J Choi, and
K S Lee
June 2009,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
H S Yoo, and
J H Suh, and
J T Lee, and
K W Kim, and
D I Kim, and
B S Kim, and
H J Choi, and
K S Lee
May 2008,
ANZ journal of surgery,
H S Yoo, and
J H Suh, and
J T Lee, and
K W Kim, and
D I Kim, and
B S Kim, and
H J Choi, and
K S Lee
March 1996,
Clinical nuclear medicine,
H S Yoo, and
J H Suh, and
J T Lee, and
K W Kim, and
D I Kim, and
B S Kim, and
H J Choi, and
K S Lee
January 2008,
HPB : the official journal of the International Hepato Pancreato Biliary Association,
H S Yoo, and
J H Suh, and
J T Lee, and
K W Kim, and
D I Kim, and
B S Kim, and
H J Choi, and
K S Lee
June 2009,
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...,
H S Yoo, and
J H Suh, and
J T Lee, and
K W Kim, and
D I Kim, and
B S Kim, and
H J Choi, and
K S Lee
January 1992,
Radiation medicine,
H S Yoo, and
J H Suh, and
J T Lee, and
K W Kim, and
D I Kim, and
B S Kim, and
H J Choi, and
K S Lee
January 2000,
Cardiovascular and interventional radiology,
