Microarray-based technology for glycomics analysis. 2012

Jingqing Gao, and Lina Ma, and Dianjun Liu, and Zhenxin Wang
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China.

In the post-genomic era, glycomics (the functional study of carbohydrates in living organisms) has come into the forefront of biological research because the interactions of glycoconjugates with proteins not only occur widely in biological processes of cells but also initiate infection of host cells by bacteria and viruses. Microarrays have been reportedly successful in carbohydrate-protein interaction as well as cellular surface glycan profiling. This review provides an overview of recent progress in the development of microarray-based techniques for glycomic studies. The fabrication, application and challenge/bottleneck of glycan/lectin microarrays have been summarized and discussed.

UI MeSH Term Description Entries
D002241 Carbohydrates A class of organic compounds composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n. The largest class of organic compounds, including STARCH; GLYCOGEN; CELLULOSE; POLYSACCHARIDES; and simple MONOSACCHARIDES. Carbohydrate
D046228 Microarray Analysis The simultaneous analysis, on a microchip, of multiple samples or targets arranged in an array format. Microarray Analytical Devices,Microarray Microchips,Nanoarray Analytical Devices,Analysis, Microarray,Analytical Device, Microarray,Analytical Device, Nanoarray,Analytical Devices, Microarray,Analytical Devices, Nanoarray,Device, Microarray Analytical,Device, Nanoarray Analytical,Devices, Microarray Analytical,Devices, Nanoarray Analytical,Microarray Analytical Device,Microarray Microchip,Microchip, Microarray,Microchips, Microarray,Nanoarray Analytical Device
D054794 Glycomics The systematic study of the structure and function of the complete set of glycans (the glycome) produced in a single organism and identification of all the genes that encode glycoproteins. Sugar Code,Glycobiology
D037102 Lectins Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition. Animal Lectin,Animal Lectins,Isolectins,Lectin,Isolectin,Lectin, Animal,Lectins, Animal

Related Publications

Jingqing Gao, and Lina Ma, and Dianjun Liu, and Zhenxin Wang
January 2010, Methods in enzymology,
Jingqing Gao, and Lina Ma, and Dianjun Liu, and Zhenxin Wang
January 2011, Nature methods,
Jingqing Gao, and Lina Ma, and Dianjun Liu, and Zhenxin Wang
December 1998, Current opinion in biotechnology,
Jingqing Gao, and Lina Ma, and Dianjun Liu, and Zhenxin Wang
January 2014, Methods in molecular biology (Clifton, N.J.),
Jingqing Gao, and Lina Ma, and Dianjun Liu, and Zhenxin Wang
January 2010, Methods in molecular biology (Clifton, N.J.),
Jingqing Gao, and Lina Ma, and Dianjun Liu, and Zhenxin Wang
January 2004, Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference,
Jingqing Gao, and Lina Ma, and Dianjun Liu, and Zhenxin Wang
November 2019, Analytical chemistry,
Jingqing Gao, and Lina Ma, and Dianjun Liu, and Zhenxin Wang
December 2005, Nihon rinsho. Japanese journal of clinical medicine,
Jingqing Gao, and Lina Ma, and Dianjun Liu, and Zhenxin Wang
April 2005, The British journal of surgery,
Jingqing Gao, and Lina Ma, and Dianjun Liu, and Zhenxin Wang
April 2018, Expert review of proteomics,
Copied contents to your clipboard!