OBJECTIVE This paper presents a model for designing, providing, and evaluating global experiential education, both local and internationally. METHODS A literature review was conducted to identify studies and models of global nursing education experiences in the scientific indexed literature and the gray literature on the Internet published by professional associations. RESULTS Key elements of the model developed include institutional and program mission and goals, global health core content, program characteristics, student characteristics, reflection, and perspective transformation. These factors combine to address the range of interweaving factors that need to be considered in providing well-designed global health offerings. CONCLUSIONS The framework is offered for use in developing global experiences and in conducting studies to advance our understanding of what and how students learn and are transformed from participation in global education.