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S1 proteins are present in the nuclear structures sensitive to DNases and RNase. To examine localization of these proteins, an antibody was raised in a rabbit. Indirect immunofluorescence staining revealed that S1 proteins located in the extranucleolar nuclear regions of quiescent myocardial and cerebellar cells as well as actively duplicating mouse 3T3 fibroblasts. They located in euchromatin regions of thymus lymphocytes, with a characteristic aster-like immunofluorescence pattern, and on the border of condensed chromatin areas by deposition of immunogold particles in ultrathin sections of thymus. Thus, S1 proteins may be in a nuclear function assigned to the border of heterochromatin areas, and other than synthesis of DNA or of ribosomal RNA. Possible involvement of S1 proteins in the extranucleolar RNA synthesis is discussed.
K P Takahashi, and
Y Higashi, and
T Uchimoto, and
T Hasuma, and
N Yamamoto, and
S Morisawa, and
A Inoue
January 1986,
Scandinavian journal of gastroenterology. Supplement,
K P Takahashi, and
Y Higashi, and
T Uchimoto, and
T Hasuma, and
N Yamamoto, and
S Morisawa, and
A Inoue
November 1994,
Acta dermato-venereologica,
K P Takahashi, and
Y Higashi, and
T Uchimoto, and
T Hasuma, and
N Yamamoto, and
S Morisawa, and
A Inoue
March 1984,
The Anatomical record,
K P Takahashi, and
Y Higashi, and
T Uchimoto, and
T Hasuma, and
N Yamamoto, and
S Morisawa, and
A Inoue
March 1992,
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology,
K P Takahashi, and
Y Higashi, and
T Uchimoto, and
T Hasuma, and
N Yamamoto, and
S Morisawa, and
A Inoue
March 1992,
Biochemistry international,
K P Takahashi, and
Y Higashi, and
T Uchimoto, and
T Hasuma, and
N Yamamoto, and
S Morisawa, and
A Inoue
January 1987,
The Histochemical journal,
K P Takahashi, and
Y Higashi, and
T Uchimoto, and
T Hasuma, and
N Yamamoto, and
S Morisawa, and
A Inoue
January 1996,
Histochemistry and cell biology,
K P Takahashi, and
Y Higashi, and
T Uchimoto, and
T Hasuma, and
N Yamamoto, and
S Morisawa, and
A Inoue
January 1987,
Acta neuropathologica,
K P Takahashi, and
Y Higashi, and
T Uchimoto, and
T Hasuma, and
N Yamamoto, and
S Morisawa, and
A Inoue
May 1977,
Cell and tissue research,
K P Takahashi, and
Y Higashi, and
T Uchimoto, and
T Hasuma, and
N Yamamoto, and
S Morisawa, and
A Inoue
November 2005,
Oncology reports,
