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As many as 72 patients with erosive and ulcerous injuries to the stomach and duodenum were examined for the clinical efficacy of antepsin (sucralfate). Of these patients, 42 were with duodenal ulcer, 10 with gastric ulcer and 20 with erosive gastroduodenitis). Antepsin exerted a beneficial effect on the painful syndrome and on ulcer and erosion healing. The coefficient of the therapeutic efficacy of antepsin in duodenal ulcer patients turned out to be equal to 2.67 that of gastric ulcer to 2.1 and that in patients with gastroduodenitis was 2.6. The drug did not produce any well-defined side effects. In some cases (8.3%), it caused the appearance or enhancement of constipation. Antepsin is indicated not only in ulcer disease but also in duodenogastric reflux, reflux gastritis and reflux esophagitis.
N E Fedorov, and
A A Laktionova, and
A V Tkachev, and
A A Iakovlev, and
L V Soboleva, and
V M Grib
April 1983,
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N E Fedorov, and
A A Laktionova, and
A V Tkachev, and
A A Iakovlev, and
L V Soboleva, and
V M Grib
August 1991,
Klinicheskaia meditsina,
N E Fedorov, and
A A Laktionova, and
A V Tkachev, and
A A Iakovlev, and
L V Soboleva, and
V M Grib
January 1989,
Klinicheskaia meditsina,
N E Fedorov, and
A A Laktionova, and
A V Tkachev, and
A A Iakovlev, and
L V Soboleva, and
V M Grib
September 1983,
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N E Fedorov, and
A A Laktionova, and
A V Tkachev, and
A A Iakovlev, and
L V Soboleva, and
V M Grib
July 1986,
Clinical pharmacy,
N E Fedorov, and
A A Laktionova, and
A V Tkachev, and
A A Iakovlev, and
L V Soboleva, and
V M Grib
August 1991,
The American journal of medicine,
N E Fedorov, and
A A Laktionova, and
A V Tkachev, and
A A Iakovlev, and
L V Soboleva, and
V M Grib
April 1984,
The Medical letter on drugs and therapeutics,
N E Fedorov, and
A A Laktionova, and
A V Tkachev, and
A A Iakovlev, and
L V Soboleva, and
V M Grib
May 1965,
Nutrition reviews,
N E Fedorov, and
A A Laktionova, and
A V Tkachev, and
A A Iakovlev, and
L V Soboleva, and
V M Grib
January 1982,
Pharmacotherapy,
N E Fedorov, and
A A Laktionova, and
A V Tkachev, and
A A Iakovlev, and
L V Soboleva, and
V M Grib
January 1982,
Clinical pharmacy,
