A fatal case of severe methemoglobinemia presumably due to chlorate ingestion. 2011

H Kinoshita, and N Yoshioka, and A Kuse, and M Nishiguchi, and N Tanaka, and M Jamal, and M Kumihashi, and Y Nagasaki, and Y Ueno, and K Ameno
Department of Forensic Medicine, Faculty of Medicine, Kagawa University, Japan. kinochin@med.kagawa-u.ac.jp

A fatal case due to severe methemoglobinemia is presented. A male in his forties was found unconscious in his house and, despite intensive care, death was confirmed approximately 11 hours later. Toxicological analysis using ion chromatography revealed the presence of chlorate in the stomach contents. However, chlorate was not detected in the blood, and no other drugs or ethanol were detected in the blood either. We concluded that the cause of death was presumably due to chlorate poisoning, based on the results of the autopsy and the toxicological examination.

UI MeSH Term Description Entries
D008297 Male Males
D008706 Methemoglobin Ferrihemoglobin
D008708 Methemoglobinemia The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed) Methemoglobinemias
D002704 Chlorates Inorganic salts of chloric acid that contain the ClO3- ion. Chlorate
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D017809 Fatal Outcome Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept. Fatal Outcomes,Outcome, Fatal,Outcomes, Fatal

Related Publications

H Kinoshita, and N Yoshioka, and A Kuse, and M Nishiguchi, and N Tanaka, and M Jamal, and M Kumihashi, and Y Nagasaki, and Y Ueno, and K Ameno
January 2000, International journal of legal medicine,
H Kinoshita, and N Yoshioka, and A Kuse, and M Nishiguchi, and N Tanaka, and M Jamal, and M Kumihashi, and Y Nagasaki, and Y Ueno, and K Ameno
January 2014, Clinical toxicology (Philadelphia, Pa.),
H Kinoshita, and N Yoshioka, and A Kuse, and M Nishiguchi, and N Tanaka, and M Jamal, and M Kumihashi, and Y Nagasaki, and Y Ueno, and K Ameno
November 2017, The New England journal of medicine,
H Kinoshita, and N Yoshioka, and A Kuse, and M Nishiguchi, and N Tanaka, and M Jamal, and M Kumihashi, and Y Nagasaki, and Y Ueno, and K Ameno
January 1980, Annals of internal medicine,
H Kinoshita, and N Yoshioka, and A Kuse, and M Nishiguchi, and N Tanaka, and M Jamal, and M Kumihashi, and Y Nagasaki, and Y Ueno, and K Ameno
March 2003, Nederlands tijdschrift voor geneeskunde,
H Kinoshita, and N Yoshioka, and A Kuse, and M Nishiguchi, and N Tanaka, and M Jamal, and M Kumihashi, and Y Nagasaki, and Y Ueno, and K Ameno
March 2003, Nederlands tijdschrift voor geneeskunde,
H Kinoshita, and N Yoshioka, and A Kuse, and M Nishiguchi, and N Tanaka, and M Jamal, and M Kumihashi, and Y Nagasaki, and Y Ueno, and K Ameno
June 2003, Nederlands tijdschrift voor geneeskunde,
H Kinoshita, and N Yoshioka, and A Kuse, and M Nishiguchi, and N Tanaka, and M Jamal, and M Kumihashi, and Y Nagasaki, and Y Ueno, and K Ameno
December 2002, Nederlands tijdschrift voor geneeskunde,
H Kinoshita, and N Yoshioka, and A Kuse, and M Nishiguchi, and N Tanaka, and M Jamal, and M Kumihashi, and Y Nagasaki, and Y Ueno, and K Ameno
April 2008, Clinical toxicology (Philadelphia, Pa.),
H Kinoshita, and N Yoshioka, and A Kuse, and M Nishiguchi, and N Tanaka, and M Jamal, and M Kumihashi, and Y Nagasaki, and Y Ueno, and K Ameno
December 1959, Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie,
Copied contents to your clipboard!