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The results of a series of experiments are interpreted to indicate that protein synthesis in reticulocyte lysates is not affected by the reticulocyte cAMP-dependent protein kinase. The catalytic subunit of this enzyme was isolated to apparent homogeneity. Also, the protein inhibitor of this protein kinase was isolated from muscle. Neither physiological concentrations of cAMP nor any of these protein components had a detectable effect on protein synthesis in reticulocyte lysates in the presence or absence of exogenous heme. Phosphorylation of the smallest subunit of eukaryotic initiation factor 2 or the 90,000 to 100,000-dalton peptide associated with eukaryotic initiation factor 2 kinase activity were not affected by the activity of the cAMP-dependent protein kinase under conditions in which exogenous heme has a pronounced effect on these reactions.
N Grankowski, and
G Kramer, and
B Hardesty
January 1973,
Intervirology,
N Grankowski, and
G Kramer, and
B Hardesty
January 1976,
The Biochemical journal,
N Grankowski, and
G Kramer, and
B Hardesty
April 1976,
The Journal of general virology,
N Grankowski, and
G Kramer, and
B Hardesty
January 1973,
Nature: New biology,
N Grankowski, and
G Kramer, and
B Hardesty
October 1987,
Applied biochemistry and biotechnology,
N Grankowski, and
G Kramer, and
B Hardesty
December 1982,
Biochemical and biophysical research communications,
N Grankowski, and
G Kramer, and
B Hardesty
February 1979,
Biochemical and biophysical research communications,
N Grankowski, and
G Kramer, and
B Hardesty
January 1985,
The International journal of biochemistry,
N Grankowski, and
G Kramer, and
B Hardesty
July 1985,
Biochimica et biophysica acta,
N Grankowski, and
G Kramer, and
B Hardesty
February 1974,
Biochemical and biophysical research communications,
