[Application of slow vertex response in auditory threshold prediction for subjects with hearing loss]. 2011

Hui Liu, and Guang-You Zhu, and Li-Hua Fan, and Xiao-Rong Zhou, and Xun-Wei Liu, and Xiao-Ping Yang
Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice,, Shanghai 200063, PR China. hhcomeon@126.com

OBJECTIVE To study the value of slow vertex response (SVR) in the evaluation of hearing loss by comparing the hearing thresholds acquired with SVR and pure tone audiometry (PTA). METHODS Twenty-five subjects (40 ears) with sensorineural hearing loss were tested by PTA and SVR. According to the thresholds of PTA, these ears were subdivided into mild, moderate and severe hearing loss groups, and rank sum test was performed on the thresholds of SVR and PTA for all the hearing loss groups. Then, the correlation between PTA thresholds and SVR thresholds was analyzed and the mathematical models were established for predicting behavioral thresholds by the thresholds of SVR. RESULTS At four test frequencies (0.5, 1, 2 and 4kHz), the thresholds of SVR had high correlations with thresholds of PTA. Four liner regression equations were established, and the correlation coefficient(r) were 0.971, 0.976, 0.957 and 0.928, respectively (P < 0.05). Back substitution test showed that the liner regression equations would be an easy method for estimating the behavior thresholds. CONCLUSIONS The behavioral threshold can be well judged and evaluated by the liner regression equations established with SVR thresholds.

UI MeSH Term Description Entries
D008297 Male Males
D011237 Predictive Value of Tests In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test. Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D012044 Regression Analysis Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable. Regression Diagnostics,Statistical Regression,Analysis, Regression,Analyses, Regression,Diagnostics, Regression,Regression Analyses,Regression, Statistical,Regressions, Statistical,Statistical Regressions
D005072 Evoked Potentials, Auditory The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS. Auditory Evoked Potentials,Auditory Evoked Response,Auditory Evoked Potential,Auditory Evoked Responses,Evoked Potential, Auditory,Evoked Response, Auditory,Evoked Responses, Auditory,Potentials, Auditory Evoked
D005260 Female Females
D005554 Forensic Medicine The application of medical knowledge to questions of law. Legal Medicine,Medicine, Forensic,Medicine, Legal
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000161 Acoustic Stimulation Use of sound to elicit a response in the nervous system. Auditory Stimulation,Stimulation, Acoustic,Stimulation, Auditory
D001300 Audiometry, Evoked Response A form of electrophysiologic audiometry in which an analog computer is included in the circuit to average out ongoing or spontaneous brain wave activity. A characteristic pattern of response to a sound stimulus may then become evident. Evoked response audiometry is known also as electric response audiometry. Audiometry, Electroencephalic Response,Electrocochleography,Evoked Response Audiometry,Audiometries, Electroencephalic Response,Audiometries, Evoked Response,Electrocochleographies,Electroencephalic Response Audiometries,Electroencephalic Response Audiometry,Evoked Response Audiometries,Response Audiometries, Electroencephalic,Response Audiometries, Evoked,Response Audiometry, Electroencephalic,Response Audiometry, Evoked
D001301 Audiometry, Pure-Tone Measurement of hearing based on the use of pure tones of various frequencies and intensities as auditory stimuli. Audiometry, Bekesy,Audiometry, Pure Tone,Bekesy Audiometry,Pure-Tone Audiometry

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