| D007031 |
Hypothalamus |
Ventral part of the DIENCEPHALON extending from the region of the OPTIC CHIASM to the caudal border of the MAMMILLARY BODIES and forming the inferior and lateral walls of the THIRD VENTRICLE. |
Lamina Terminalis,Preoptico-Hypothalamic Area,Area, Preoptico-Hypothalamic,Areas, Preoptico-Hypothalamic,Preoptico Hypothalamic Area,Preoptico-Hypothalamic Areas |
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| D009478 |
Neuropeptide Y |
A 36-amino acid peptide present in many organs and in many sympathetic noradrenergic neurons. It has vasoconstrictor and natriuretic activity and regulates local blood flow, glandular secretion, and smooth muscle activity. The peptide also stimulates feeding and drinking behavior and influences secretion of pituitary hormones. |
Neuropeptide Y-Like Immunoreactive Peptide,Neuropeptide Tyrosine,Neuropeptide Y Like Immunoreactive Peptide,Tyrosine, Neuropeptide |
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| D009765 |
Obesity |
A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). |
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| D001835 |
Body Weight |
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. |
Body Weights,Weight, Body,Weights, Body |
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| D004435 |
Eating |
The consumption of edible substances. |
Dietary Intake,Feed Intake,Food Intake,Macronutrient Intake,Micronutrient Intake,Nutrient Intake,Nutritional Intake,Ingestion,Dietary Intakes,Feed Intakes,Intake, Dietary,Intake, Feed,Intake, Food,Intake, Macronutrient,Intake, Micronutrient,Intake, Nutrient,Intake, Nutritional,Macronutrient Intakes,Micronutrient Intakes,Nutrient Intakes,Nutritional Intakes |
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| D005947 |
Glucose |
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement. |
Dextrose,Anhydrous Dextrose,D-Glucose,Glucose Monohydrate,Glucose, (DL)-Isomer,Glucose, (alpha-D)-Isomer,Glucose, (beta-D)-Isomer,D Glucose,Dextrose, Anhydrous,Monohydrate, Glucose |
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| D000077153 |
Progranulins |
Cysteine-rich, precursor glycoproteins encoded by the granulin gene (GRN). They contain granulin-repeats separated by linker sequences that are cleaved by a variety of proteases to release the individual GRANULIN PEPTIDES. The mammalian progranulin is composed of a half-granulin repeat followed by 7 granulin repeats. The mammalian GRANULINS are named PARAGRANULIN and granulin 1-7 for their order in the progranulin propeptide. Progranulin has growth-factor like effects and is expressed over a broad range of tissues. Under-expression of progranulin is linked to neurodegenerative diseases including FRONTOTEMPORAL DEMENTIA and NEURONAL CEROID LIPOFUSCINOSIS, while over-expression is linked to metabolic diseases including OBESITY, and INSULIN RESISTANCE. |
Acrogranin,Granulin Precursor,Granulin Precursor Protein,PC Cell-Derived Growth Factor,Proepithelin,Progranulin,PC Cell Derived Growth Factor |
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| D000077155 |
Granulins |
Small, cysteine-rich peptides generated by the proteolytic cleavage of progranulin. Granulin peptides are each composed of a granulin-motif, while paragranulin is composed of a half-granulin motif. The mammalian granulins are named granulin 1-7 for their sequence order in the progranulin propeptide, and are alternately named granulin G, F, B, A, C, D, and E; or epithelin 7, 6, 2, 1, 3, 4, and 5, i.e. granulin 1 aka granulin G aka epithelin 7, etc. |
Epithelin,Granulin,Epithelin 1,Epithelin 2,Epithelin 3,Epithelin 4,Epithelin 5,Epithelin-1,Epithelin-2,Epithelin2,Epithelins,Granulin (123-179),Granulin (206-261),Granulin 1,Granulin 2,Granulin 3,Granulin 4,Granulin 5,Granulin 6,Granulin 7,Granulin A,Granulin B,Granulin C,Granulin D,Granulin E,Granulin F,Granulin G,Granulin Peptide (281-336),Granulin Peptide (58 -113),Granulin Peptides,Granulin-3,Granulin3,Paragranulin,5, Granulin |
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| D000818 |
Animals |
Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. |
Animal,Metazoa,Animalia |
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| D001069 |
Appetite Regulation |
Physiologic mechanisms which regulate or control the appetite and food intake. |
Food Intake Regulation,Intake Regulation, Food,Regulation, Appetite,Regulation, Food Intake,Appetite Regulations,Food Intake Regulations,Intake Regulations, Food,Regulations, Appetite,Regulations, Food Intake |
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