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Results of morphological, cytochemical and immunological studies performed in adult acute leukaemias have been compared. Thirty one cases proved to be acute myeloid leukaemia, while 25 cases were shown to be acute lymphoid leukaemia. Based on our results we conclude that immunophenotyping with monoclonal antibodies does not help in distinguishing the subtypes of AML. For purposes of clinical diagnosis cytochemical methods are valuable. On the other hand the monoclonal antibodies are essential in distinguishing the very immature myeloid and lymphoid leukaemias and this is of great importance from the clinical point of view, in determining therapy. Moreover, the diagnosis of acute lymphoid leukaemias is not possible without the specific monoclonal antibodies. Their application is first of all in haematological centers caring for leukaemia patients nowadays already obligatory. Gene rearrangement studies make the diagnosis more accurate and help in the diagnosis of leukaemias of unknown immunological origin.
K Pálóczi, and
K Natonek, and
A Mód, and
A Poros, and
R Mihalik, and
J Földi, and
M Benczur, and
Z Hollán
September 1984,
Medicina clinica,
K Pálóczi, and
K Natonek, and
A Mód, and
A Poros, and
R Mihalik, and
J Földi, and
M Benczur, and
Z Hollán
June 1973,
National Cancer Institute monograph,
K Pálóczi, and
K Natonek, and
A Mód, and
A Poros, and
R Mihalik, and
J Földi, and
M Benczur, and
Z Hollán
July 1987,
American journal of clinical pathology,
K Pálóczi, and
K Natonek, and
A Mód, and
A Poros, and
R Mihalik, and
J Földi, and
M Benczur, and
Z Hollán
May 1991,
American journal of clinical pathology,
K Pálóczi, and
K Natonek, and
A Mód, and
A Poros, and
R Mihalik, and
J Földi, and
M Benczur, and
Z Hollán
January 1978,
Bibliotheca haematologica,
K Pálóczi, and
K Natonek, and
A Mód, and
A Poros, and
R Mihalik, and
J Földi, and
M Benczur, and
Z Hollán
January 1967,
Laboratornoe delo,
K Pálóczi, and
K Natonek, and
A Mód, and
A Poros, and
R Mihalik, and
J Földi, and
M Benczur, and
Z Hollán
September 1966,
Schweizerische medizinische Wochenschrift,
K Pálóczi, and
K Natonek, and
A Mód, and
A Poros, and
R Mihalik, and
J Földi, and
M Benczur, and
Z Hollán
March 1984,
The Indian journal of medical research,
K Pálóczi, and
K Natonek, and
A Mód, and
A Poros, and
R Mihalik, and
J Földi, and
M Benczur, and
Z Hollán
January 1979,
Medical and pediatric oncology,
K Pálóczi, and
K Natonek, and
A Mód, and
A Poros, and
R Mihalik, and
J Földi, and
M Benczur, and
Z Hollán
October 1984,
Cancer research,
