-transparent.png){kind=logo}
There is considerable evidence that at least some cases of juvenile onset diabetes mellitus in humans are a result of viral infection. Viral-induced diabetes in mice may provide an experimental counterpart more similar to the clinical situation than chemical-induced diabetes. Our experiments in such mice indicate that islet transplantation is effective in ameliorating viral-induced diabetes and is encouraging for ultimate clinical application of islet transplantation to juvenile onset insulin-dependent diabetics. In addition, our results show that islets in ectopic sites outside of the pancreas are resistant to damage induced by primary viral infection. The mechanism of this resistance is obscure and will be the subject of future investigations.
R J Howard, and
H H Balfour, and
A J Matas, and
J S Najarian, and
D E Sutherland
October 1980,
The Journal of experimental medicine,
R J Howard, and
H H Balfour, and
A J Matas, and
J S Najarian, and
D E Sutherland
November 1968,
Science (New York, N.Y.),
R J Howard, and
H H Balfour, and
A J Matas, and
J S Najarian, and
D E Sutherland
April 1987,
Experientia,
R J Howard, and
H H Balfour, and
A J Matas, and
J S Najarian, and
D E Sutherland
January 1978,
Surgical forum,
R J Howard, and
H H Balfour, and
A J Matas, and
J S Najarian, and
D E Sutherland
January 1989,
Contributions to nephrology,
R J Howard, and
H H Balfour, and
A J Matas, and
J S Najarian, and
D E Sutherland
January 1987,
Reviews of infectious diseases,
R J Howard, and
H H Balfour, and
A J Matas, and
J S Najarian, and
D E Sutherland
November 1983,
Infection and immunity,
R J Howard, and
H H Balfour, and
A J Matas, and
J S Najarian, and
D E Sutherland
June 1984,
Transplantation proceedings,
R J Howard, and
H H Balfour, and
A J Matas, and
J S Najarian, and
D E Sutherland
April 1987,
Fortschritte der Medizin,
R J Howard, and
H H Balfour, and
A J Matas, and
J S Najarian, and
D E Sutherland
May 1973,
The Journal of experimental medicine,
