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[Radial immunodiffusion study of foot-and-mouth disease virus type A]. 1978

P Tekerlekov

The radial immunodiffusion(RI), was used to study F. M. D. viruses, type A. It was found that the specific linkage between F. M. D. antigens and antibodies could be demonstrated through RI with the formation of precipitation circles. It was demonstrated that specific reactions were produced when homologus or heterologus antigens and sera of one and the same F. M. D. virus type interacted. The size of the precipitation circles proved inversely proportional to the concentration of antibodies in the homologous systems. It was also established that RI could be made use of in the demonstration of some subtype differences between the F. M. D. antigens of type A. Discussed is the problem of RI sensitivity as well as the possibility of using this technique for the early diagnosis of the F. M. D. infection and the study of the F. M. D. viruses.

UI MeSH Term Description Entries
D005537 Aphthovirus A genus of the family PICORNAVIRIDAE infecting mainly cloven-hoofed animals. They cause vesicular lesions and upper respiratory tract infections. FOOT AND MOUTH DISEASE VIRUS is the type species. Equine rhinitis A virus,Equine rhinovirus 1,Aphthoviruses
D005779 Immunodiffusion Technique involving the diffusion of antigen or antibody through a semisolid medium, usually agar or agarose gel, with the result being a precipitin reaction. Gel Diffusion Tests,Diffusion Test, Gel,Diffusion Tests, Gel,Gel Diffusion Test,Immunodiffusions,Test, Gel Diffusion,Tests, Gel Diffusion
D000914 Antibodies, Viral Immunoglobulins produced in response to VIRAL ANTIGENS. Viral Antibodies
D000956 Antigens, Viral Substances elaborated by viruses that have antigenic activity. Viral Antigen,Viral Antigens,Antigen, Viral
D012703 Serotyping Process of determining and distinguishing species of bacteria or viruses based on antigens they share. Serotypings

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