Screening for bipolar disorder among outpatients with substance use disorders. 2013

A Nallet, and B Weber, and S Favre, and M Gex-Fabry, and R Voide, and F Ferrero, and D Zullino, and Y Khazaal, and J M Aubry
Geneva University Hospital, Department of Mental Health and Psychiatry, Service of General Psychiatry, Bipolar Program, 6-8, rue du 31-Décembre, 1207 Geneva, Switzerland.

BACKGROUND Comorbidity of bipolar disorder and alcohol or substance abuse/dependence is frequent and has marked negative consequences on the course of the illness and treatment compliance. The objective of this study was to compare the validity of two short instruments aimed at screening bipolar disorders among patients treated for substance use disorders. METHODS The Mood Disorder Questionnaire (MDQ) and the Hypomania Checklist-32 (HCL-32) were tested with reference to the mood section of the Structured Clinical Interview for DSM-IV axis I disorders (SCID) in 152 patients, recruited in two outpatient clinics providing specialized treatment for alcohol and opiate dependence. RESULTS According to the SCID, 33 patients (21.7%) had a diagnosis within the bipolar spectrum (two bipolar I, 21 bipolar II and 10 bipolar not otherwise specified). The HCL-32 was more sensitive (90.9% vs. 66.7%) and the MDQ more specific (38.7% vs. 77.3%) for the whole sample. The MDQ displayed higher sensitivity and specificity in patients treated for alcohol than for opiate dependence, whereas the HCL-32 was highly sensitive but poorly specific in both samples. Both instruments had a positive predictive value under 50%. CONCLUSIONS Caution is needed when using the MDQ and HCL-32 in patients treated for substance use disorders.

UI MeSH Term Description Entries
D007406 Interview, Psychological A directed conversation aimed at eliciting information for psychiatric diagnosis, evaluation, treatment planning, etc. The interview may be conducted by a social worker or psychologist. Interview, Psychologic,Interviews, Psychological,Psychological Interview,Psychological Interviews,Interviews, Psychologic,Psychologic Interview,Psychologic Interviews
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009293 Opioid-Related Disorders Disorders related to or resulting from abuse or misuse of OPIOIDS. Opiate Addiction,Opiate Dependence,Opioid Misuse,Opioid Use Disorder,Prescription Opioid Abuse,Prescription Opioid Misuse,Addiction, Opioid,Dependence, Opioid,Opiate Abuse,Opioid Abuse,Opioid Addiction,Opioid Dependence,Abuse, Opiate,Abuse, Opioid,Abuse, Prescription Opioid,Addiction, Opiate,Dependence, Opiate,Disorder, Opioid Use,Misuse, Opioid,Misuse, Prescription Opioid,Opiate Abuses,Opioid Abuse, Prescription,Opioid Abuses,Opioid Addictions,Opioid Dependences,Opioid Misuses,Opioid Related Disorders,Opioid Use Disorders,Opioid-Related Disorder,Prescription Opioid Abuses,Prescription Opioid Misuses
D011569 Psychiatric Status Rating Scales Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness. Factor Construct Rating Scales (FCRS),Katz Adjustment Scales,Lorr's Inpatient Multidimensional Psychiatric Rating Scale,Wittenborn Scales,Edinburgh Postnatal Depression Scale,Mini International Neuropsychiatric Interview
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000437 Alcoholism A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4) Alcohol Abuse,Alcoholic Intoxication, Chronic,Ethanol Abuse,Alcohol Addiction,Alcohol Dependence,Alcohol Use Disorder,Abuse, Alcohol,Abuse, Ethanol,Addiction, Alcohol,Alcohol Use Disorders,Chronic Alcoholic Intoxication,Dependence, Alcohol,Intoxication, Chronic Alcoholic,Use Disorders, Alcohol

Related Publications

A Nallet, and B Weber, and S Favre, and M Gex-Fabry, and R Voide, and F Ferrero, and D Zullino, and Y Khazaal, and J M Aubry
April 2004, Journal of substance abuse treatment,
A Nallet, and B Weber, and S Favre, and M Gex-Fabry, and R Voide, and F Ferrero, and D Zullino, and Y Khazaal, and J M Aubry
January 2010, The American journal on addictions,
A Nallet, and B Weber, and S Favre, and M Gex-Fabry, and R Voide, and F Ferrero, and D Zullino, and Y Khazaal, and J M Aubry
June 2008, Bipolar disorders,
A Nallet, and B Weber, and S Favre, and M Gex-Fabry, and R Voide, and F Ferrero, and D Zullino, and Y Khazaal, and J M Aubry
July 2022, Journal of clinical medicine,
A Nallet, and B Weber, and S Favre, and M Gex-Fabry, and R Voide, and F Ferrero, and D Zullino, and Y Khazaal, and J M Aubry
March 2010, The Journal of clinical psychiatry,
A Nallet, and B Weber, and S Favre, and M Gex-Fabry, and R Voide, and F Ferrero, and D Zullino, and Y Khazaal, and J M Aubry
August 2012, Drug and alcohol dependence,
A Nallet, and B Weber, and S Favre, and M Gex-Fabry, and R Voide, and F Ferrero, and D Zullino, and Y Khazaal, and J M Aubry
March 1998, General hospital psychiatry,
A Nallet, and B Weber, and S Favre, and M Gex-Fabry, and R Voide, and F Ferrero, and D Zullino, and Y Khazaal, and J M Aubry
August 2018, Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent,
A Nallet, and B Weber, and S Favre, and M Gex-Fabry, and R Voide, and F Ferrero, and D Zullino, and Y Khazaal, and J M Aubry
April 1998, The Journal of clinical psychiatry,
A Nallet, and B Weber, and S Favre, and M Gex-Fabry, and R Voide, and F Ferrero, and D Zullino, and Y Khazaal, and J M Aubry
November 2004, Journal of the American Academy of Child and Adolescent Psychiatry,
Copied contents to your clipboard!