Biomaterial Database

Eosinophilic granuloma. The management of solitary lesions of bone. 1990

P E Greis, and F M Hankin

Section of Orthopaedic Surgery, University of Michigan, Ann Arbor.

Solitary eosinophilic granuloma (EG) lesions of bone can represent diagnostic and treatment dilemmas for the orthopedic surgeon. A retrospective review of one institution's experience with isolated EG skeletal lesions over a 30-year period was undertaken. Solitary lesions responded well to most treatment modalities (e.g., curettage, excision, and irradiation) and infrequently resulted in functional impairment. While EG involvement in bone can be a manifestation of a systemic histiocytosis, single-focus skeletal involvement appears to be a benign pathophysiologic process.

UI	MeSH Term	Description	Entries
D011859	Radiography	Examination of any part of the body for diagnostic purposes by means of X-RAYS or GAMMA RAYS, recording the image on a sensitized surface (such as photographic film).	Radiology, Diagnostic X-Ray,Roentgenography,X-Ray, Diagnostic,Diagnostic X-Ray,Diagnostic X-Ray Radiology,X-Ray Radiology, Diagnostic,Diagnostic X Ray,Diagnostic X Ray Radiology,Diagnostic X-Rays,Radiology, Diagnostic X Ray,X Ray Radiology, Diagnostic,X Ray, Diagnostic,X-Rays, Diagnostic
D001847	Bone Diseases	Diseases of BONES.	Bone Disease,Disease, Bone,Diseases, Bone
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D003475	Curettage	A scraping, usually of the interior of a cavity or tract, for removal of new growth or other abnormal tissue, or to obtain material for tissue diagnosis. It is performed with a curet (curette), a spoon-shaped instrument designed for that purpose. (From Stedman, 25th ed & Dorland, 27th ed)	Curettages
D003646	Debridement	The removal of foreign material and devitalized or contaminated tissue from or adjacent to a traumatic or infected lesion until surrounding healthy tissue is exposed. (Dorland, 27th ed)	Debridements
D004803	Eosinophilic Granuloma	The most benign and common form of Langerhans-cell histiocytosis which involves localized nodular lesions predominantly of the bones but also of the gastric mucosa, small intestine, lungs, or skin, with infiltration by EOSINOPHILS.	Granuloma, Eosinophilic,Eosinophilic Granulomas,Granulomas, Eosinophilic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective