BIOMAT Database Logo BIOMAT Database Logo

Does continuous positive airway pressure compensate for loss of glottic function during tracheal intubation? 1990

R A Smith, and M Johnson, and B Venus
Department of Anesthesiology, University of South Florida College of Medicine, Tampa 33612.

Adult patients with acute lung injury (ALI) exhibit increased PaO2 when receiving continuous positive airway pressure (CPAP). Some have increased PaO2 after extubation. To determine the role a competent glottis played in improving gas exchange, we anesthetized seven rabbits and inserted central venous and carotid artery catheters. After recovery from anesthesia, ALI was induced with oleic acid (0.08 ml/kg). Twenty-four hours later, the animals were sedated and placed in a sling. The pHa and blood gas tensions were measured. The animals were placed supine and were given inhalation anesthesia to facilitate tracheal intubation. A polyethylene catheter was placed slightly distal to the tracheal tube outlet to measure tracheal pressure (PT). Intubated rabbits were repositioned in the sling and were given either zero end-expiratory pressure (ZEEP) or 5 cm H2O CPAP, alternately. After the animals had breathed room air for 60 min, pHa and blood gas tensions were again measured, and PT was recorded. Animals were extubated, but the PT catheter was left in place. Data were collected again 60 min later, the catheter was removed, and the animals were returned to their cages. Forty-eight hours after onset of ALI, the protocol was repeated.(ABSTRACT TRUNCATED AT 250 WORDS)

UI MeSH Term Description Entries
D007442 Intubation, Intratracheal A procedure involving placement of a tube into the trachea through the mouth or nose in order to provide a patient with oxygen and anesthesia. Intubation, Endotracheal,Endotracheal Intubation,Endotracheal Intubations,Intratracheal Intubation,Intratracheal Intubations,Intubations, Endotracheal,Intubations, Intratracheal
D011175 Positive-Pressure Respiration A method of mechanical ventilation in which pressure is maintained to increase the volume of gas remaining in the lungs at the end of expiration, thus reducing the shunting of blood through the lungs and improving gas exchange. Positive End-Expiratory Pressure,Positive-Pressure Ventilation,End-Expiratory Pressure, Positive,End-Expiratory Pressures, Positive,Positive End Expiratory Pressure,Positive End-Expiratory Pressures,Positive Pressure Respiration,Positive Pressure Ventilation,Positive-Pressure Respirations,Positive-Pressure Ventilations,Pressure, Positive End-Expiratory,Pressures, Positive End-Expiratory,Respiration, Positive-Pressure,Respirations, Positive-Pressure,Ventilation, Positive-Pressure,Ventilations, Positive-Pressure
D011659 Pulmonary Gas Exchange The exchange of OXYGEN and CARBON DIOXIDE between alveolar air and pulmonary capillary blood that occurs across the BLOOD-AIR BARRIER. Exchange, Pulmonary Gas,Gas Exchange, Pulmonary
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D012128 Respiratory Distress Syndrome A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA. ARDS, Human,Acute Respiratory Distress Syndrome,Adult Respiratory Distress Syndrome,Pediatric Respiratory Distress Syndrome,Respiratory Distress Syndrome, Acute,Respiratory Distress Syndrome, Adult,Respiratory Distress Syndrome, Pediatric,Shock Lung,Distress Syndrome, Respiratory,Distress Syndromes, Respiratory,Human ARDS,Lung, Shock,Respiratory Distress Syndromes,Syndrome, Respiratory Distress
D004195 Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. Animal Disease Model,Animal Disease Models,Disease Model, Animal
D005931 Glottis The vocal apparatus of the larynx, situated in the middle section of the larynx. Glottis consists of the VOCAL FOLDS and an opening (rima glottidis) between the folds. Rima Glottidis,Glottidi, Rima,Glottidis, Rima,Rima Glottidi
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

Related Publications

R A Smith, and M Johnson, and B Venus
Continuous positive airway pressure without tracheal intubation in spontaneously breathing patients.
May 1976, Chest,
R A Smith, and M Johnson, and B Venus
Oropharyngeal continuous positive airway pressure: An alternative to intubation for newborns not applied nasal continuous positive airway pressure.
August 2016, Indian journal of anaesthesia,
R A Smith, and M Johnson, and B Venus
Cracking loss of continuous positive airway pressure.
February 2002, Paediatric anaesthesia,
R A Smith, and M Johnson, and B Venus
Intraocular Pressure during Continuous Positive Airway Pressure.
January 2017, Medical principles and practice : international journal of the Kuwait University, Health Science Centre,
R A Smith, and M Johnson, and B Venus
Continuous positive airway pressure does not improve lung function after cardiac surgery.
September 2006, Canadian journal of anaesthesia = Journal canadien d'anesthesie,
R A Smith, and M Johnson, and B Venus
Using tracheal pressure to trigger the ventilator and control airway pressure during continuous positive airway pressure decreases work of breathing.
August 1995, Chest,
R A Smith, and M Johnson, and B Venus
Nasal Continuous Positive Airway Pressure During Intubation in Superobese Patients Prolongs Safe Apnea Period.
July 2019, Anesthesia and analgesia,
R A Smith, and M Johnson, and B Venus
Continuous positive airway pressure during neonatal resuscitation.
March 2006, Clinics in perinatology,
R A Smith, and M Johnson, and B Venus
Humidification during continuous positive airway pressure therapy.
March 2000, Chest,
R A Smith, and M Johnson, and B Venus
Flow-by during continuous positive airway pressure.
March 1991, Critical care medicine,
Copied contents to your clipboard!