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Diabetes insipidus and two consecutive pregnancies: a case report and review of the literature. 2011
G Adonakis, and
V Kyriazopoulou, and
G Androutsopoulos, and
V Papadopoulos, and
G Decavalas, and
N A Georgopoulos
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Patras, Medical School, Rion, Greece. adonakisgeorgios@hotmail.com
We report a case of a woman with a preexisting diabetes insipidus (DI), who had two consecutive uncomplicated pregnancies. Both pregnancies resulted after spontaneous conception and had a similar uneventful course. At the time of conception the patient was receiving 1-desamino-8D-arginine-vasopressin (DDAVP) 30 microg/d which maintained a urinary volume of 2-3 l/day. Pre-existing DI can be handled carefully and result in an uncomplicated pregnancy. In such cases careful monitoring of the patient's fluid balance and liver enzymes, as well as monitoring for pre-eclampsia and oligohydramnios during pregnancy are essential.
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