Maternal and neonatal outcomes following induction of labor: a cohort study. 2012

Rosalie M Grivell, and Aimee J Reilly, and Helena Oakey, and Annabelle Chan, and Jodie M Dodd
Discipline of Obstetrics and Gynaecology, University of Adelaide, South Australia, Australia. rosalie.grivell@adelaide.edu.au

OBJECTIVE To evaluate maternal and neonatal outcomes associated with birth at term by week of gestational age and also by onset of labor. METHODS Cohort study. METHODS A state-wide perinatal outcome database. METHODS 28,626 women with spontaneous onset of labor, induction of labor for recognized indications and induction of labor for non-recognized indications. METHODS Cohort study utilizing a validated dataset comparing outcomes with type of onset of labor using a log binomial model. METHODS Cesarean section, assisted vaginal birth, important measures of maternal and neonatal morbidity. RESULTS Induction of labor for non-recognized indications was associated with a significantly increased risk of a range of outcomes, including cesarean section (RR 1.67, 95% CI 1.55-1.80). The lowest risk of adverse maternal and infant outcome occurred with birth between 38 and 39 weeks and with the spontaneous onset of labor. CONCLUSIONS Induction of labor for non-recognized indications at term is associated with an increased risk of adverse outcomes. Caution is warranted with a liberal policy of induction of labor at term in an otherwise uncomplicated pregnancy.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007744 Obstetric Labor Complications Medical problems associated with OBSTETRIC LABOR, such as BREECH PRESENTATION; PREMATURE OBSTETRIC LABOR; HEMORRHAGE; or others. These complications can affect the well-being of the mother, the FETUS, or both. Complications, Labor,Labor Complications,Complication, Labor,Complication, Obstetric Labor,Complications, Obstetric Labor,Labor Complication,Labor Complication, Obstetric,Labor Complications, Obstetric,Obstetric Labor Complication
D007751 Labor, Induced Artificially induced UTERINE CONTRACTION. Induced Labor,Induction of Labor,Labor Induced,Labor Induction,Induced, Labor,Induction, Labor,Inductions, Labor,Labor Inductions
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011256 Pregnancy Outcome Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; or SPONTANEOUS ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO. Outcome, Pregnancy,Outcomes, Pregnancy,Pregnancy Outcomes
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D001720 Birth Injuries Mechanical or anoxic trauma incurred by the infant during labor or delivery. Injuries, Birth,Birth Injury,Injury, Birth
D001724 Birth Weight The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms. Birthweight,Birth Weights,Birthweights,Weight, Birth,Weights, Birth
D002585 Cesarean Section Extraction of the FETUS by means of abdominal HYSTEROTOMY. Abdominal Delivery,Delivery, Abdominal,C-Section (OB),Caesarean Section,Postcesarean Section,Abdominal Deliveries,C Section (OB),C-Sections (OB),Caesarean Sections,Cesarean Sections,Deliveries, Abdominal
D005113 Extraction, Obstetrical Extraction of the fetus by means of obstetrical instruments. Extraction, Obstetric,Extractions, Obstetric,Extractions, Obstetrical,Obstetric Extraction,Obstetric Extractions,Obstetrical Extraction,Obstetrical Extractions

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